Entity Details

Primary name PHLP2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6ZVD8
EntryNamePHLP2_HUMAN
FullNamePH domain leucine-rich repeat-containing protein phosphatase 2
TaxID9606
Evidenceevidence at protein level
Length1323
SequenceStatuscomplete
DateCreated2005-06-07
DateModified2021-06-02

Ontological Relatives

GenesPHLPP2

GO terms

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GOName
GO:0004722 protein serine/threonine phosphatase activity
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0007165 signal transduction
GO:0016020 membrane
GO:0043231 intracellular membrane-bounded organelle
GO:0045171 intercellular bridge
GO:0046872 metal ion binding
GO:0051898 negative regulation of protein kinase B signaling
GO:0072686 mitotic spindle
GO:0106306 protein serine phosphatase activity
GO:0106307 protein threonine phosphatase activity

Subcellular Location

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Subcellular Location
Cytoplasm
Membrane
Nucleus

Domains

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DomainNameCategoryType
IPR001611 Leucine-rich repeatRepeatRepeat
IPR001932 PPM-type phosphatase domainDomainDomain
IPR003591 Leucine-rich repeat, typical subtypeRepeatRepeat
IPR032675 Leucine-rich repeat domain superfamilyFamilyHomologous superfamily
IPR036457 PPM-type phosphatase domain superfamilyFamilyHomologous superfamily

Diseases

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