Entity Details

Primary name SRGP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ7Z6B7
EntryNameSRGP1_HUMAN
FullNameSLIT-ROBO Rho GTPase-activating protein 1
TaxID9606
Evidenceevidence at protein level
Length1085
SequenceStatuscomplete
DateCreated2004-06-07
DateModified2021-06-02

Ontological Relatives

GenesSRGAP1

GO terms

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GOName
GO:0005096 GTPase activator activity
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0007165 signal transduction
GO:0030336 negative regulation of cell migration
GO:0043547 positive regulation of GTPase activity
GO:0051056 regulation of small GTPase mediated signal transduction

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000198 Rho GTPase-activating protein domainDomainDomain
IPR001060 FCH domainDomainDomain
IPR001452 SH3 domainDomainDomain
IPR008936 Rho GTPase activation proteinFamilyHomologous superfamily
IPR027267 AH/BAR domain superfamilyFamilyHomologous superfamily
IPR031160 F-BAR domainDomainDomain
IPR035648 srGAP1/2/3, SH3 domainDomainDomain
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily
IPR037451 SLIT-ROBO Rho GTPase-activating protein 1, F-BAR domainDomainDomain

Diseases

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