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Entity Details
Primary name
SIRB1_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
O00241
EntryName
SIRB1_HUMAN
FullName
Signal-regulatory protein beta-1
TaxID
9606
Evidence
evidence at protein level
Length
398
SequenceStatus
complete
DateCreated
2002-09-19
DateModified
2021-06-02
Ontological Relatives
Genes
SIRPB1
GO terms
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GO
Name
GO:0005886
plasma membrane
GO:0005887
integral component of plasma membrane
GO:0007165
signal transduction
GO:0007166
cell surface receptor signaling pathway
GO:0009986
cell surface
GO:0030667
secretory granule membrane
GO:0043312
neutrophil degranulation
GO:0045087
innate immune response
GO:0050766
positive regulation of phagocytosis
GO:0050870
positive regulation of T cell activation
Subcellular Location
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Subcellular Location
Cell membrane
Domains
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Domain
Name
Category
Type
IPR003597
Immunoglobulin C1-set
Domain
Domain
IPR003599
Immunoglobulin subtype
Domain
Domain
IPR007110
Immunoglobulin-like domain
Domain
Domain
IPR013106
Immunoglobulin V-set domain
Domain
Domain
IPR013783
Immunoglobulin-like fold
Family
Homologous superfamily
IPR036179
Immunoglobulin-like domain superfamily
Family
Homologous superfamily
Diseases
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Drugs
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Interactions
9 interactions
Interactor
Partner
Sources
Publications
Link
SIRB1_HUMAN
DAB1_HUMAN
BioGRID, IntAct
25416956
details
SIRB1_HUMAN
MEOX2_HUMAN
BioGRID, IntAct
25416956
details
SIRB1_HUMAN
RBPMS_HUMAN
BioGRID, IntAct
25416956
details
SIRB1_HUMAN
RFOX1_HUMAN
BioGRID, IntAct
32296183
details
SIRB1_HUMAN
APOC1_HUMAN
BioGRID, IntAct
32296183
details
SIRB1_HUMAN
BPIA1_HUMAN
BioGRID, IntAct
32296183
details
SIRB1_HUMAN
CD47_HUMAN
IntAct
17070842
details
SIRB1_HUMAN
TYOBP_HUMAN
BioGRID, HPRD, IntAct
10604985
10940905
details
SIRB1_HUMAN
SIRB1_HUMAN
HPRD
16081415
details
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