Entity Details

Primary name RGS12_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO14924
EntryNameRGS12_HUMAN
FullNameRegulator of G-protein signaling 12
TaxID9606
Evidenceevidence at protein level
Length1447
SequenceStatuscomplete
DateCreated1998-12-15
DateModified2021-06-02

Ontological Relatives

GenesRGS12

GO terms

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GOName
GO:0000794 condensed nuclear chromosome
GO:0005096 GTPase activator activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007186 G protein-coupled receptor signaling pathway
GO:0008277 regulation of G protein-coupled receptor signaling pathway
GO:0009968 negative regulation of signal transduction
GO:0016363 nuclear matrix
GO:0030425 dendrite
GO:0030695 GTPase regulator activity
GO:0045202 synapse

Subcellular Location

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Subcellular Location
Cell junction
Cell projection
Cytoplasm
Nucleus
Nucleus matrix

Domains

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DomainNameCategoryType
IPR001478 PDZ domainDomainDomain
IPR003109 GoLoco motifSiteConserved site
IPR003116 Raf-like Ras-bindingDomainDomain
IPR006020 PTB/PI domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR016137 RGS domainDomainDomain
IPR024066 RGS, subdomain 1/3FamilyHomologous superfamily
IPR029071 Ubiquitin-like domain superfamilyFamilyHomologous superfamily
IPR036034 PDZ superfamilyFamilyHomologous superfamily
IPR036305 RGS domain superfamilyFamilyHomologous superfamily
IPR037880 RGS12, RGS domainDomainDomain

Diseases

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