Entity Details

Primary name MK13_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO15264
EntryNameMK13_HUMAN
FullNameMitogen-activated protein kinase 13
TaxID9606
Evidenceevidence at protein level
Length365
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesMAPK13

GO terms

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GOName
GO:0004674 protein serine/threonine kinase activity
GO:0004707 MAP kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006970 response to osmotic stress
GO:0007049 cell cycle
GO:0018105 peptidyl-serine phosphorylation
GO:0032755 positive regulation of interleukin-6 production
GO:0034644 cellular response to UV
GO:0035556 intracellular signal transduction
GO:0050729 positive regulation of inflammatory response
GO:0051403 stress-activated MAPK cascade
GO:0070301 cellular response to hydrogen peroxide
GO:0071347 cellular response to interleukin-1
GO:0072709 cellular response to sorbitol
GO:0072740 cellular response to anisomycin
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1903936 cellular response to sodium arsenite

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR003527 Mitogen-activated protein (MAP) kinase, conserved siteSiteConserved site
IPR008352 Mitogen-activated protein (MAP) kinase p38-likeFamilyFamily
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR038785 Mitogen-activated protein kinase 13FamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB01017 MinocyclineDrugbanksmall molecule
DB05157 KC706Drugbanksmall molecule
DB12010 FostamatinibDrugbanksmall molecule