Entity Details

Primary name PIDD1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9HB75
EntryNamePIDD1_HUMAN
FullNamep53-induced death domain-containing protein 1
TaxID9606
Evidenceevidence at protein level
Length910
SequenceStatuscomplete
DateCreated2006-07-11
DateModified2021-06-02

Ontological Relatives

GenesPIDD1

GO terms

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GOName
GO:0004175 endopeptidase activity
GO:0005123 death receptor binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0006915 apoptotic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006974 cellular response to DNA damage stimulus
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0007165 signal transduction
GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors
GO:0016540 protein autoprocessing
GO:0042981 regulation of apoptotic process
GO:0043065 positive regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092 positive regulation of NF-kappaB transcription factor activity

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000488 Death domainDomainDomain
IPR000906 ZU5 domainDomainDomain
IPR001611 Leucine-rich repeatRepeatRepeat
IPR003591 Leucine-rich repeat, typical subtypeRepeatRepeat
IPR011029 Death-like domain superfamilyFamilyHomologous superfamily
IPR019502 Peptidase S68, piddFamilyFamily
IPR032675 Leucine-rich repeat domain superfamilyFamilyHomologous superfamily

Diseases

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