Entity Details

Primary name TPSN_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO15533
EntryNameTPSN_HUMAN
FullNameTapasin
TaxID9606
Evidenceevidence at protein level
Length448
SequenceStatuscomplete
DateCreated2001-01-24
DateModified2021-06-02

Ontological Relatives

GenesTAPBP

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0002398 MHC class Ib protein complex assembly
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
GO:0006955 immune response
GO:0010468 regulation of gene expression
GO:0015433 ABC-type peptide antigen transporter activity
GO:0016021 integral component of membrane
GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I
GO:0030670 phagocytic vesicle membrane
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane
GO:0042288 MHC class I protein binding
GO:0042605 peptide antigen binding
GO:0042824 MHC class I peptide loading complex
GO:0046978 TAP1 binding
GO:0046979 TAP2 binding
GO:0050823 peptide antigen stabilization
GO:0051082 unfolded protein binding
GO:0061635 regulation of protein complex stability
GO:0062061 TAP complex binding
GO:0065003 protein-containing complex assembly
GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane
GO:1990668 vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR003597 Immunoglobulin C1-setDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR008056 TapasinFamilyFamily
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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