Entity Details

Primary name NUAK1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO60285
EntryNameNUAK1_HUMAN
FullNameNUAK family SNF1-like kinase 1
TaxID9606
Evidenceevidence at protein level
Length661
SequenceStatuscomplete
DateCreated2001-06-20
DateModified2021-06-02

Ontological Relatives

GenesNUAK1

GO terms

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GOName
GO:0001650 fibrillar center
GO:0002039 p53 binding
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006468 protein phosphorylation
GO:0006974 cellular response to DNA damage stimulus
GO:0007155 cell adhesion
GO:0015630 microtubule cytoskeleton
GO:0030155 regulation of cell adhesion
GO:0035507 regulation of myosin-light-chain-phosphatase activity
GO:0035556 intracellular signal transduction
GO:0042127 regulation of cell population proliferation
GO:0042149 cellular response to glucose starvation
GO:0046872 metal ion binding
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1901796 regulation of signal transduction by p53 class mediator
GO:2000772 regulation of cellular senescence

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site

Diseases

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Drugs

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DrugNameSourceType
DB12010 FostamatinibDrugbanksmall molecule