Entity Details

Primary name UNC5C_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95185
EntryNameUNC5C_HUMAN
FullNameNetrin receptor UNC5C
TaxID9606
Evidenceevidence at protein level
Length931
SequenceStatuscomplete
DateCreated2004-10-11
DateModified2021-06-02

Ontological Relatives

GenesUNC5C

GO terms

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GOName
GO:0005042 netrin receptor activity
GO:0005043 netrin receptor activity involved in chemorepulsion
GO:0005886 plasma membrane
GO:0006915 apoptotic process
GO:0007411 axon guidance
GO:0007420 brain development
GO:0009986 cell surface
GO:0015631 tubulin binding
GO:0016021 integral component of membrane
GO:0019901 protein kinase binding
GO:0030027 lamellipodium
GO:0030175 filopodium
GO:0030334 regulation of cell migration
GO:0030425 dendrite
GO:0030426 growth cone
GO:0033564 anterior/posterior axon guidance
GO:0043025 neuronal cell body
GO:0043065 positive regulation of apoptotic process
GO:0045202 synapse
GO:0061643 chemorepulsion of axon
GO:1990791 dorsal root ganglion development

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cell projection
Cell surface

Domains

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DomainNameCategoryType
IPR000488 Death domainDomainDomain
IPR000884 Thrombospondin type-1 (TSP1) repeatRepeatRepeat
IPR000906 ZU5 domainDomainDomain
IPR003598 Immunoglobulin subtype 2DomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR011029 Death-like domain superfamilyFamilyHomologous superfamily
IPR013098 Immunoglobulin I-setDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR033772 UPA domainDomainDomain
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily
IPR036383 Thrombospondin type-1 (TSP1) repeat superfamilyFamilyHomologous superfamily
IPR037936 Netrin receptor UNC5FamilyFamily
IPR042154 UNC5C, death domainDomainDomain

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
UNC5C_HUMANNET1_HUMANDIP, HPRD12810718 18719102 details
UNC5C_HUMANTBB3_HUMANUniProt28483977 details
UNC5C_HUMANDAPK1_HUMANBioGRID, HPRD15729359 details