Entity Details

Primary name FMNL1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95466
EntryNameFMNL1_HUMAN
FullNameFormin-like protein 1
TaxID9606
Evidenceevidence at protein level
Length1100
SequenceStatuscomplete
DateCreated2002-04-16
DateModified2021-06-02

Ontological Relatives

GenesFMNL1

GO terms

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GOName
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005938 cell cortex
GO:0008360 regulation of cell shape
GO:0016020 membrane
GO:0016477 cell migration
GO:0030866 cortical actin cytoskeleton organization
GO:0031267 small GTPase binding
GO:0032059 bleb
GO:0032794 GTPase activating protein binding
GO:0045335 phagocytic vesicle
GO:0051014 actin filament severing
GO:0051015 actin filament binding
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection
Cytoplasm
Cytoplasmic vesicle

Domains

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DomainNameCategoryType
IPR010472 Formin, FH3 domainDomainDomain
IPR010473 Formin, GTPase-binding domainDomainDomain
IPR014767 Diaphanous autoregulatory (DAD) domainDomainDomain
IPR014768 Rho GTPase-binding/formin homology 3 (GBD/FH3) domainDomainDomain
IPR015425 Formin, FH2 domainDomainDomain
IPR016024 Armadillo-type foldFamilyHomologous superfamily
IPR027657 Formin-like protein 1FamilyFamily
IPR042201 Formin, FH2 domain superfamilyFamilyHomologous superfamily
IPR043592 Formin-like proteinFamilyFamily

Diseases

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