Entity Details

Primary name FGF1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP05230
EntryNameFGF1_HUMAN
FullNameFibroblast growth factor 1
TaxID9606
Evidenceevidence at protein level
Length155
SequenceStatuscomplete
DateCreated1987-08-13
DateModified2021-06-02

Ontological Relatives

GenesFGF1

GO terms

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GOName
GO:0072163 mesonephric epithelium development
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0001934 positive regulation of protein phosphorylation
GO:0005576 extracellular region
GO:0060681 branch elongation involved in ureteric bud branching
GO:0001759 organ induction
GO:0005938 cell cortex
GO:0030334 regulation of cell migration
GO:0031012 extracellular matrix
GO:0009887 animal organ morphogenesis
GO:0030544 Hsp70 protein binding
GO:0008284 positive regulation of cell population proliferation
GO:0000187 obsolete activation of MAPK activity
GO:0051781 positive regulation of cell division
GO:0010628 positive regulation of gene expression
GO:2000347 positive regulation of hepatocyte proliferation
GO:0034605 cellular response to heat
GO:0042060 wound healing
GO:0051897 positive regulation of protein kinase B signaling
GO:0001525 angiogenesis
GO:0045542 positive regulation of cholesterol biosynthetic process
GO:0005615 extracellular space
GO:0008201 heparin binding
GO:0043406 positive regulation of MAP kinase activity
GO:0050679 positive regulation of epithelial cell proliferation
GO:2000544 regulation of endothelial cell chemotaxis to fibroblast growth factor
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0010595 positive regulation of endothelial cell migration
GO:0030154 cell differentiation
GO:0030324 lung development
GO:0005829 cytosol
GO:0030335 positive regulation of cell migration
GO:0005737 cytoplasm
GO:0007165 signal transduction
GO:0007275 multicellular organism development
GO:0005634 nucleus
GO:1902533 positive regulation of intracellular signal transduction
GO:0005104 fibroblast growth factor receptor binding
GO:0005730 nucleolus
GO:0009653 anatomical structure morphogenesis
GO:0032148 activation of protein kinase B activity
GO:0044548 S100 protein binding
GO:1901509 regulation of endothelial tube morphogenesis
GO:0000165 MAPK cascade
GO:0008083 growth factor activity
GO:0045766 positive regulation of angiogenesis
GO:1903672 positive regulation of sprouting angiogenesis
GO:0005178 integrin binding
GO:0005654 nucleoplasm

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus
Secreted

Domains

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DomainNameCategoryType
IPR002209 Fibroblast growth factor familyFamilyFamily
IPR008996 Cytokine IL1/FGFFamilyHomologous superfamily
IPR028210 Fibroblast growth factor 1FamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB00686 Pentosan polysulfateDrugbanksmall molecule
DB01025 AmlexanoxDrugbanksmall molecule
DB01109 HeparinDrugbanksmall molecule
DB01901 SucrosofateDrugbanksmall molecule
DB01942 Formic acidDrugbanksmall molecule
DB02264 O2-Sulfo-Glucuronic AcidDrugbanksmall molecule
DB03959 N,O6-Disulfo-GlucosamineDrugbanksmall molecule
DB04409 Naphthalene TrisulfonateDrugbanksmall molecule
DB06589 PazopanibDrugbanksmall molecule
DB08238 5-aminonaphthalene-2-sulfonic acidDrugbanksmall molecule
DB10770 Foreskin fibroblast (neonatal)Drugbankbiotech
DB10772 Foreskin keratinocyte (neonatal)Drugbankbiotech