Entity Details

Primary name IFIT1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP09914
EntryNameIFIT1_HUMAN
FullNameInterferon-induced protein with tetratricopeptide repeats 1
TaxID9606
Evidenceevidence at protein level
Length478
SequenceStatuscomplete
DateCreated1989-07-01
DateModified2021-06-02

Ontological Relatives

GenesIFIT1

GO terms

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GOName
GO:0003723 RNA binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0009615 response to virus
GO:0016032 viral process
GO:0019060 intracellular transport of viral protein in host cell
GO:0032091 negative regulation of protein binding
GO:0043657 host cell
GO:0045070 positive regulation of viral genome replication
GO:0045071 negative regulation of viral genome replication
GO:0050688 regulation of defense response to virus
GO:0051097 negative regulation of helicase activity
GO:0051607 defense response to virus
GO:0060337 type I interferon signaling pathway
GO:0071357 cellular response to type I interferon
GO:0071360 cellular response to exogenous dsRNA
GO:0140374 antiviral innate immune response

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR011990 Tetratricopeptide-like helical domain superfamilyFamilyHomologous superfamily
IPR019734 Tetratricopeptide repeatRepeatRepeat
IPR024121 Interferon-induced protein with tetratricopeptide repeats 1-likeFamilyFamily

Diseases

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