Entity Details

Primary name CCL4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP13236
EntryNameCCL4_HUMAN
FullNameC-C motif chemokine 4
TaxID9606
Evidenceevidence at protein level
Length92
SequenceStatuscomplete
DateCreated1990-01-01
DateModified2021-06-02

Ontological Relatives

GenesCCL4L1
CCL4

GO terms

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GOName
GO:0002548 monocyte chemotaxis
GO:0005125 cytokine activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0007155 cell adhesion
GO:0007163 establishment or maintenance of cell polarity
GO:0007165 signal transduction
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007267 cell-cell signaling
GO:0008009 chemokine activity
GO:0009615 response to virus
GO:0009636 response to toxic substance
GO:0019221 cytokine-mediated signaling pathway
GO:0030593 neutrophil chemotaxis
GO:0031726 CCR1 chemokine receptor binding
GO:0031730 CCR5 chemokine receptor binding
GO:0042802 identical protein binding
GO:0043547 positive regulation of GTPase activity
GO:0043922 negative regulation by host of viral transcription
GO:0048020 CCR chemokine receptor binding
GO:0048245 eosinophil chemotaxis
GO:0048247 lymphocyte chemotaxis
GO:0050850 positive regulation of calcium-mediated signaling
GO:0051928 positive regulation of calcium ion transport
GO:0070098 chemokine-mediated signaling pathway
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071346 cellular response to interferon-gamma
GO:0071347 cellular response to interleukin-1
GO:0071356 cellular response to tumor necrosis factor
GO:2000503 positive regulation of natural killer cell chemotaxis

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000827 CC chemokine, conserved siteSiteConserved site
IPR001811 Chemokine interleukin-8-like domainDomainDomain
IPR036048 Chemokine interleukin-8-like superfamilyFamilyHomologous superfamily
IPR039809 Chemokine beta/gamma/deltaFamilyFamily

Diseases

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Interactions

31 interactions

InteractorPartnerSourcesPublicationsLink
CCL4_HUMANCCL4_HUMANBioGRID, HPRD, MINT20959807 8134838 details
CCL4_HUMANIDE_HUMANMINT20959807 details
CCL4_HUMANZNT2_HUMANBioGRID, IntAct25416956 31515488 32296183 details
CCL4_HUMANSL7A1_HUMANBioGRID, IntAct32296183 details
CCL4_HUMANTA2R5_HUMANBioGRID, IntAct32296183 details
CCL4_HUMANSOAT_HUMANBioGRID, IntAct32296183 details
CCL4_HUMANT179B_HUMANBioGRID, IntAct32296183 details
CCL4_HUMANCXA8_HUMANBioGRID, IntAct32296183 details
CCL4_HUMANMRM1_HUMANBioGRID, IntAct32296183 details
CCL4_HUMANGPC5D_HUMANBioGRID, IntAct32296183 details
CCL4_HUMANCNR2_HUMANBioGRID, IntAct32296183 details
CCL4_HUMANZNT8_HUMANBioGRID, IntAct32296183 details
CCL4_HUMANVMAT1_HUMANBioGRID, IntAct32296183 details
CCL4_HUMANMARH2_HUMANBioGRID, IntAct32296183 details
CCL4_HUMANTM14B_HUMANBioGRID, IntAct32296183 details
CCL4_HUMANTM86B_HUMANBioGRID, IntAct32296183 details
CCL4_HUMANGP152_HUMANBioGRID, IntAct32296183 details
CCL4_HUMANTIDC1_HUMANBioGRID, IntAct32296183 details
CCL4_HUMANUN93A_HUMANBioGRID, IntAct32296183 details
CCL4_HUMANAR13B_HUMANBioGRID, IntAct32296183 details
CCL4_HUMANTMM31_HUMANBioGRID32296183 details
CCL4_HUMANCCL2_HUMANBioGRID28381538 details
CCL4_HUMANCXL13_HUMANBioGRID28381538 details
CCL4_HUMANPF4V_HUMANBioGRID28381538 details
CCL4_HUMANCCL3_HUMANBioGRID, HPRD11278300 details
CCL4_HUMANCCR1_HUMANHPRD7594543 details
CCL4_HUMANCCR5_HUMANHPRD12427015 8663314 details
CCL4_HUMANCCR8_HUMANHPRD9521068 details
CCL4_HUMANACKR2_HUMANHPRD9405404 details
CCL4_HUMANCCR3_HUMANHPRD7622448 details
CCL4_HUMANIL8_HUMANHPRD8077676 details