Entity Details

Primary name IL11_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP20809
EntryNameIL11_HUMAN
FullNameInterleukin-11
TaxID9606
Evidenceevidence at protein level
Length199
SequenceStatuscomplete
DateCreated1991-02-01
DateModified2021-06-02

Ontological Relatives

GenesIL11

GO terms

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GOName
GO:0005125 cytokine activity
GO:0005142 interleukin-11 receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0008083 growth factor activity
GO:0008284 positive regulation of cell population proliferation
GO:0019221 cytokine-mediated signaling pathway
GO:0030183 B cell differentiation
GO:0030219 megakaryocyte differentiation
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0043410 positive regulation of MAPK cascade
GO:0045444 fat cell differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046888 negative regulation of hormone secretion
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR009079 Four-helical cytokine-like, coreFamilyHomologous superfamily
IPR020412 Interleukin-11, mammalianFamilyFamily
IPR020438 Interleukin-11FamilyFamily

Diseases

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