Entity Details

Primary name IDS_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP22304
EntryNameIDS_HUMAN
FullNameIduronate 2-sulfatase
TaxID9606
Evidenceevidence at protein level
Length550
SequenceStatuscomplete
DateCreated1991-08-01
DateModified2021-06-02

Ontological Relatives

GenesIDS

GO terms

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GOName
GO:0004423 iduronate-2-sulfatase activity
GO:0005509 calcium ion binding
GO:0005764 lysosome
GO:0006027 glycosaminoglycan catabolic process
GO:0008484 sulfuric ester hydrolase activity
GO:0030207 chondroitin sulfate catabolic process
GO:0043202 lysosomal lumen

Subcellular Location

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Subcellular Location
Lysosome

Domains

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DomainNameCategoryType
IPR000917 Sulfatase, N-terminalDomainDomain
IPR017850 Alkaline-phosphatase-like, core domain superfamilyFamilyHomologous superfamily
IPR024607 Sulfatase, conserved siteSiteConserved site
IPR035874 Iduronate-2-sulfataseFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB09301 Chondroitin sulfateDrugbanksmall molecule

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
IDS_HUMAN5HT6R_HUMANBioGRID, MINT28298427 details
IDS_HUMANFOS_HUMANIntAct20195357 details
IDS_HUMANDISC1_HUMANIntAct31413325 details