Entity Details

Primary name RFA3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP35244
EntryNameRFA3_HUMAN
FullNameReplication protein A 14 kDa subunit
TaxID9606
Evidenceevidence at protein level
Length121
SequenceStatuscomplete
DateCreated1994-02-01
DateModified2021-06-02

Ontological Relatives

GenesRPA3

GO terms

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GOName
GO:0000723 telomere maintenance
GO:0000724 double-strand break repair via homologous recombination
GO:0003684 damaged DNA binding
GO:0003697 single-stranded DNA binding
GO:0005654 nucleoplasm
GO:0005662 DNA replication factor A complex
GO:0006260 DNA replication
GO:0006270 DNA replication initiation
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0006284 base-excision repair
GO:0006287 base-excision repair, gap-filling
GO:0006289 nucleotide-excision repair
GO:0006293 nucleotide-excision repair, preincision complex stabilization
GO:0006294 nucleotide-excision repair, preincision complex assembly
GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion
GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion
GO:0006297 nucleotide-excision repair, DNA gap filling
GO:0006298 mismatch repair
GO:0007346 regulation of mitotic cell cycle
GO:0019985 translesion synthesis
GO:0032201 telomere maintenance via semi-conservative replication
GO:0033683 nucleotide-excision repair, DNA incision
GO:0035861 site of double-strand break
GO:0036297 interstrand cross-link repair
GO:0042127 regulation of cell population proliferation
GO:0042276 error-prone translesion synthesis
GO:0042769 DNA damage response, detection of DNA damage
GO:0070987 error-free translesion synthesis
GO:1900034 regulation of cellular response to heat
GO:1901796 regulation of signal transduction by p53 class mediator

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR012340 Nucleic acid-binding, OB-foldFamilyHomologous superfamily
IPR013970 Replication factor A protein 3FamilyFamily

Diseases

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Interactions

27 interactions

InteractorPartnerSourcesPublicationsLink
RFA3_HUMANRFA1_HUMANBioGRID, DIP, HPRD, IntAct, MINT, UniProt11927569 12527904 19338310 20811460 21504906 2159011 22939629 24126761 24981860 26344197 26474068 26496610 27723720 7760808 9461578 details
RFA3_HUMANRFA2_HUMANBioGRID, HPRD, IntAct, MINT, UniProt10449415 10982866 11081631 11173472 11927569 15965237 19338310 22939629 24126761 24981860 26186194 26344197 28514442 8663296 9461578 details
RFA3_HUMANACTB_HUMANBioGRID, IntAct19338310 24332808 details
RFA3_HUMANRAD51_HUMANBioGRID, IntAct19338310 details
RFA3_HUMANRFWD3_HUMANBioGRID, MINT21504906 21558276 24126761 24332808 28575658 29576527 details
RFA3_HUMANRFA4_HUMANBioGRID, HPRD, IntAct, UniProt26186194 28514442 7760808 details
RFA3_HUMANMCM2_HUMANBioGRID, HPRD12614612 details
RFA3_HUMANATRIP_HUMANBioGRID23723247 24332808 details
RFA3_HUMANCDC5L_HUMANBioGRID24332808 details
RFA3_HUMANPRP19_HUMANBioGRID24332808 details
RFA3_HUMANERCC1_HUMANBioGRID24036546 details
RFA3_HUMANBLM_HUMANBioGRID, MINT, UniProt12724401 15775963 24126761 24332808 30279242 details
RFA3_HUMANTRAF6_HUMANIntAct17353931 details
RFA3_HUMANMOFA1_HUMANIntAct17353931 details
RFA3_HUMANHLAB_HUMANIntAct17353931 details
RFA3_HUMANRAD52_HUMANBioGRID, IntAct, MINT19338310 24126761 details
RFA3_HUMANWRN_HUMANBioGRID, IntAct, MINT24126761 24332808 27173435 30279242 unassigned1312 details
RFA3_HUMANSMAL1_HUMANBioGRID, MINT24126761 24332808 29576527 details
RFA3_HUMANDPOLL_HUMANBioGRID, IntAct27173435 unassigned1312 details
RFA3_HUMANSP16H_HUMANBioGRID, IntAct27173435 unassigned1312 details
RFA3_HUMANRFA3_HUMANBioGRID, HPRD11927569 24126761 details
RFA3_HUMANPRI1_HUMANBioGRID17035231 details
RFA3_HUMANPCNA_HUMANBioGRID11254741 details
RFA3_HUMANHERC2_HUMANBioGRID22261722 30279242 details
RFA3_HUMANFBH1_HUMANBioGRID23319600 24332808 details
RFA3_HUMANZUP1_HUMANBioGRID29476094 29563501 29576527 details
RFA3_HUMANETAA1_HUMANBioGRID27723720 details