Entity Details

Primary name LSS_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP48449
EntryNameLSS_HUMAN
FullNameLanosterol synthase
TaxID9606
Evidenceevidence at protein level
Length732
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesLSS

GO terms

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GOName
GO:0000250 lanosterol synthase activity
GO:0005789 endoplasmic reticulum membrane
GO:0005811 lipid droplet
GO:0006694 steroid biosynthetic process
GO:0006695 cholesterol biosynthetic process
GO:0016020 membrane
GO:0016104 triterpenoid biosynthetic process
GO:0019216 regulation of lipid metabolic process
GO:0031647 regulation of protein stability
GO:0042300 beta-amyrin synthase activity

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR002365 Terpene synthase, conserved siteSiteConserved site
IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroidFamilyHomologous superfamily
IPR018333 Squalene cyclaseFamilyFamily
IPR032696 Squalene cyclase, C-terminalDomainDomain
IPR032697 Squalene cyclase, N-terminalDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB02016 R048-8071Drugbanksmall molecule
DB03696 LanosterolDrugbanksmall molecule