Entity Details

Primary name NUCB2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP80303
EntryNameNUCB2_HUMAN
FullNameNucleobindin-2
TaxID9606
Evidenceevidence at protein level
Length420
SequenceStatuscomplete
DateCreated1994-02-01
DateModified2021-06-02

Ontological Relatives

GenesNUCB2

GO terms

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GOName
GO:0001965 G-protein alpha-subunit binding
GO:0003677 DNA binding
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005509 calcium ion binding
GO:0005615 extracellular space
GO:0005635 nuclear envelope
GO:0005783 endoplasmic reticulum
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007264 small GTPase mediated signal transduction
GO:0032099 negative regulation of appetite
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cytoplasm
Endoplasmic reticulum
Golgi apparatus
Membrane
Nucleus envelope
Secreted

Domains

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DomainNameCategoryType
IPR002048 EF-hand domainDomainDomain
IPR011992 EF-hand domain pairFamilyHomologous superfamily
IPR018247 EF-Hand 1, calcium-binding siteSiteBinding site
IPR028813 Nucleobindin-2FamilyFamily
IPR040250 NucleobindinFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB11093 Calcium citrateDrugbanksmall molecule
DB11348 Calcium PhosphateDrugbanksmall molecule
DB14481 Calcium phosphate dihydrateDrugbanksmall molecule