Entity Details

Primary name GSDME
Entity type gene
Source Source Link

Details

PrimaryID1687
RefseqGeneNG_011593
SymbolGSDME
Namegasdermin E
Chromosome7
Location7p15.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1996-03-12
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsGSDME_HUMAN

GO terms

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GOName
GO:0002839 positive regulation of immune response to tumor cell
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007605 sensory perception of sound
GO:0008219 cell death
GO:0008285 negative regulation of cell population proliferation
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0022829 wide pore channel activity
GO:0043410 positive regulation of MAPK cascade
GO:0060113 inner ear receptor cell differentiation
GO:0070265 necrotic cell death
GO:0070269 pyroptosis
GO:0071356 cellular response to tumor necrosis factor
GO:0098586 cellular response to virus
GO:0140507 granzyme-mediated programmed cell death signaling pathway
GO:1901612 cardiolipin binding
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway

Diseases

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Interactions

22 interactions

InteractorPartnerSourcesPublicationsLink
GSDMEPTNBioGRID, HPRD, IntAct16169070 details
GSDMEITGB1BP1BioGRID, IntAct23414517 details
GSDMETIFABioGRID, IntAct32296183 details
GSDMEEGFRBioGRID23956138 details
GSDMESNW1BioGRID, MINT20467437 details
GSDMECDC5LBioGRID, MINT20467437 details
GSDMERUSF1BioGRID, IntAct28514442 details
GSDMESIGLECL1BioGRID, IntAct28514442 details
GSDMEEPHA1BioGRID, IntAct28514442 details
GSDMESCN2BBioGRID, IntAct26186194 28514442 details
GSDMEMRS2BioGRID, IntAct28514442 details
GSDMEMUL1BioGRID, IntAct28514442 details
GSDMEPLECBioGRID, IntAct28514442 details
GSDMERPS3BioGRID, IntAct28514442 details
GSDMESLC27A2BioGRID, IntAct28514442 details
GSDMEGPAT4BioGRID, IntAct28514442 details
GSDMEZSCAN29BioGRID, IntAct28514442 details
GSDMEBIRC6BioGRID26186194 details
GSDMENTRK1BioGRID25921289 details
GSDMEGBF1BioGRID31519766 details
GSDMEKIF14BioGRID31586073 details
GSDMEAPEX1BioGRID28986522 details