Entity Details

Primary name APOA1
Entity type gene
Source Source Link

Details

PrimaryID335
RefseqGeneNG_012021
SymbolAPOA1
Nameapolipoprotein A1
Chromosome11
Location11q23.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1989-02-21
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsAPOA1_HUMAN

GO terms

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GOName
GO:0001523 retinoid metabolic process
GO:0001540 amyloid-beta binding
GO:0001932 regulation of protein phosphorylation
GO:0001935 endothelial cell proliferation
GO:0002576 platelet degranulation
GO:0002719 negative regulation of cytokine production involved in immune response
GO:0005102 signaling receptor binding
GO:0005543 phospholipid binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005769 early endosome
GO:0005788 endoplasmic reticulum lumen
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006656 phosphatidylcholine biosynthetic process
GO:0006695 cholesterol biosynthetic process
GO:0006869 lipid transport
GO:0006898 receptor-mediated endocytosis
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007229 integrin-mediated signaling pathway
GO:0007584 response to nutrient
GO:0008035 high-density lipoprotein particle binding
GO:0008203 cholesterol metabolic process
GO:0008211 glucocorticoid metabolic process
GO:0009986 cell surface
GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0010873 positive regulation of cholesterol esterification
GO:0010875 positive regulation of cholesterol efflux
GO:0010898 positive regulation of triglyceride catabolic process
GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling
GO:0014012 peripheral nervous system axon regeneration
GO:0015485 cholesterol binding
GO:0018158 protein oxidation
GO:0018206 peptidyl-methionine modification
GO:0019222 regulation of metabolic process
GO:0019899 enzyme binding
GO:0019915 lipid storage
GO:0030139 endocytic vesicle
GO:0030300 regulation of intestinal cholesterol absorption
GO:0030301 cholesterol transport
GO:0030325 adrenal gland development
GO:0031072 heat shock protein binding
GO:0031100 animal organ regeneration
GO:0031210 phosphatidylcholine binding
GO:0031410 cytoplasmic vesicle
GO:0032489 regulation of Cdc42 protein signal transduction
GO:0032691 negative regulation of interleukin-1 beta production
GO:0033344 cholesterol efflux
GO:0033700 phospholipid efflux
GO:0034115 negative regulation of heterotypic cell-cell adhesion
GO:0034190 apolipoprotein receptor binding
GO:0034191 apolipoprotein A-I receptor binding
GO:0034361 very-low-density lipoprotein particle
GO:0034362 low-density lipoprotein particle
GO:0034363 intermediate-density lipoprotein particle
GO:0034364 high-density lipoprotein particle
GO:0034365 discoidal high-density lipoprotein particle
GO:0034366 spherical high-density lipoprotein particle
GO:0034371 chylomicron remodeling
GO:0034372 very-low-density lipoprotein particle remodeling
GO:0034375 high-density lipoprotein particle remodeling
GO:0034378 chylomicron assembly
GO:0034380 high-density lipoprotein particle assembly
GO:0034384 high-density lipoprotein particle clearance
GO:0034774 secretory granule lumen
GO:0035025 positive regulation of Rho protein signal transduction
GO:0042157 lipoprotein metabolic process
GO:0042158 lipoprotein biosynthetic process
GO:0042493 response to drug
GO:0042627 chylomicron
GO:0042632 cholesterol homeostasis
GO:0042802 identical protein binding
GO:0043534 blood vessel endothelial cell migration
GO:0043627 response to estrogen
GO:0043687 post-translational protein modification
GO:0043691 reverse cholesterol transport
GO:0044267 cellular protein metabolic process
GO:0045499 chemorepellent activity
GO:0045723 positive regulation of fatty acid biosynthetic process
GO:0046470 phosphatidylcholine metabolic process
GO:0046889 positive regulation of lipid biosynthetic process
GO:0050728 negative regulation of inflammatory response
GO:0050766 positive regulation of phagocytosis
GO:0050821 protein stabilization
GO:0050919 negative chemotaxis
GO:0051006 positive regulation of lipoprotein lipase activity
GO:0051180 vitamin transport
GO:0051345 positive regulation of hydrolase activity
GO:0051496 positive regulation of stress fiber assembly
GO:0055091 phospholipid homeostasis
GO:0055102 lipase inhibitor activity
GO:0060192 negative regulation of lipase activity
GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity
GO:0060354 negative regulation of cell adhesion molecule production
GO:0060761 negative regulation of response to cytokine stimulus
GO:0062023 collagen-containing extracellular matrix
GO:0070062 extracellular exosome
GO:0070328 triglyceride homeostasis
GO:0070508 cholesterol import
GO:0070653 high-density lipoprotein particle receptor binding
GO:0071682 endocytic vesicle lumen
GO:0072562 blood microparticle
GO:0120020 cholesterol transfer activity
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading
GO:1902995 positive regulation of phospholipid efflux
GO:1903561 extracellular vesicle
GO:1990000 amyloid fibril formation

Diseases

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Interactions

120 interactions

InteractorPartnerSourcesPublicationsLink
APOA1MAP7D1BioGRID, HPRD, IntAct16169070 details
APOA1TNFRSF10CBioGRID, HPRD, IntAct16169070 details
APOA1TOMM20BioGRID, HPRD, IntAct16169070 details
APOA1PCMT1HPRD, IntAct16169070 details
APOA1APPBioGRID, IntAct11297421 21832049 32814053 7802646 details
APOA1APOC1BioGRID, IntAct11991719 15174051 details
APOA1CLEC4GBioGRID, IntAct18624398 details
APOA1HPBioGRID, MINT15533931 19758344 24981860 details
APOA1FBLN1BioGRID, IntAct21988832 details
APOA1POLR1HBioGRID, IntAct21988832 details
APOA1AKT2BioGRID, IntAct21988832 details
APOA1JAK3BioGRID, IntAct21988832 details
APOA1SPP1BioGRID, IntAct21988832 details
APOA1MAPK6BioGRID, IntAct, MINT21900206 28514442 details
APOA1APOA1BioGRID, DIP, HPRD, IntAct, MINT11744719 15174051 17676061 18719128 20133843 20884842 22184756 22609356 24316228 24702826 8810909 9003180 9200714 9356442 details
APOA1SCARB1bhf-ucl, BioGRID, HPRD1076467 10764676 details
APOA1ABCA1bhf-ucl, BioGRID, HPRD, IntAct12084722 27017521 30458687 details
APOA1LCATbhf-ucl, BioGRID, DIP, HPRD10026251 10222237 15654758 1587806 1644835 17676061 3104518 4335615 details
APOA1CMTM5BioGRID, IntAct25416956 25910212 32296183 details
APOA1BRAPBioGRID, IntAct25820252 details
APOA1LAMP2IntAct32814053 details
APOA1SH3GLB1IntAct32814053 details
APOA1PDE1ABioGRID, HPRD11991719 details
APOA1PLTPBioGRID, HPRD11854286 9469594 details
APOA1GPLD1BioGRID, HPRD11254757 details
APOA1SAA2BioGRID11991719 details
APOA1NAXEBioGRID, HPRD11991719 details
APOA1ABCA13BioGRID11162594 details
APOA1VKORC1BioGRID21103663 details
APOA1APOA2BioGRID10722751 24981860 3104518 details
APOA1NDRG1BioGRID15922294 details
APOA1TREM2BioGRID27477018 details
APOA1HSP90AA1BioGRID31273033 details
APOA1TTRBioGRID, HPRD, IntAct10627502 15174051 details
APOA1SNCABioGRID, IntAct28887769 31270237 details
APOA1C1QBPIntAct28565870 details
APOA1APOBBioGRID, HPRD, IntAct19164805 28183703 7592581 details
APOA1APOL1BioGRID9325276 details
APOA1APOFBioGRID, HPRD6816269 details
APOA1LBPBioGRID, HPRD8663389 details
APOA1CD40LGBioGRID10085035 details
APOA1VCPBioGRID19164805 details
APOA1DGAT1BioGRID3104518 details
APOA1APODBioGRID3104518 details
APOA1ATP4ABioGRID17255364 details
APOA1U2AF2BioGRID26641092 details
APOA1CETPHPRD9305883 details
APOA1PON1HPRD16128586 details
APOA1CFHR1HPRD8663389 details
APOA1ATP5F1BHPRD2687158 details
APOA1HPRHPRD10085035 details
APOA1FAM83CBioGRID, IntAct15174051 details
APOA1QDPRBioGRID, IntAct15174051 details
APOA1CPBioGRID, IntAct15174051 details
APOA1RRP1BBioGRID, IntAct15174051 details
APOA1ROBO3BioGRID, IntAct15174051 details
APOA1FN1BioGRID, IntAct15174051 details
APOA1CTSLBioGRID, IntAct15174051 details
APOA1MOCOSBioGRID, IntAct15174051 details
APOA1SPEF2BioGRID, IntAct15174051 details
APOA1KRT1BioGRID, IntAct15174051 details
APOA1TNS3BioGRID, IntAct15174051 details
APOA1PTPN5BioGRID, IntAct15174051 details
APOA1NLRP1BioGRID, IntAct15174051 details
APOA1SMPDL3ABioGRID, IntAct15174051 details
APOA1CLUBioGRID, IntAct15174051 details
APOA1C1QABioGRID, IntAct15174051 details
APOA1KIAA0754BioGRID, IntAct15174051 details
APOA1APOC3BioGRID, IntAct15174051 details
APOA1PDE4BBioGRID, IntAct15174051 details
APOA1TXNDC2BioGRID, IntAct15174051 details
APOA1FGABioGRID, IntAct15174051 25241761 details
APOA1HBA1BioGRID, IntAct15174051 details
APOA1HBA2IntAct15174051 details
APOA1SETXBioGRID, IntAct15174051 details
APOA1KRT9BioGRID, IntAct15174051 details
APOA1ABCA6BioGRID, IntAct15174051 details
APOA1SAFB2BioGRID, IntAct15174051 details
APOA1DNTTBioGRID, IntAct15174051 details
APOA1C1QCBioGRID, IntAct15174051 details
APOA1SERTAD3BioGRID, IntAct15174051 details
APOA1FAM169ABioGRID, IntAct15174051 details
APOA1CNMDBioGRID, IntAct15174051 details
APOA1KRT16BioGRID, IntAct15174051 details
APOA1ALBBioGRID, IntAct15174051 details
APOA1TFBioGRID, IntAct15174051 24981860 details
APOA1MIS12BioGRID, IntAct20360068 details
APOA1CD81BioGRID, IntAct30024968 32900848 details
APOA1SNX27BioGRID, IntAct28514442 details
APOA1DDX31BioGRID, IntAct28514442 details
APOA1DDX19BBioGRID, IntAct26186194 28514442 details
APOA1UPF3ABioGRID, IntAct28514442 details
APOA1ALDH2BioGRID, IntAct26186194 28514442 details
APOA1ZNF558BioGRID, IntAct26186194 28514442 details
APOA1GDPD1BioGRID, IntAct26186194 28514442 details
APOA1GOT1L1BioGRID, IntAct28514442 details
APOA1VCAM1BioGRID, IntAct28514442 details
APOA1TMEM43BioGRID, IntAct28514442 details
APOA1HYPKBioGRID, MINT24981860 details
APOA1NSD2BioGRID, MINT24981860 details
APOA1TEX101BioGRID, UniProt30097533 details
APOA1UCHL5BioGRID21800051 details
APOA1ESR2BioGRID29509190 details
APOA1TET2BioGRID29735542 details
APOA1EYA1BioGRID28675297 details
APOA1CUL7BioGRID31343991 details
APOA1FANCD2BioGRID31180492 details
APOA1TRIM6BioGRID31992359 details
APOA1USP15BioGRID31952546 details
APOA1STATHBioGRID24981860 details
APOA1HBBBioGRID24981860 details
APOA1LCN1BioGRID24981860 details
APOA1PRR4BioGRID24981860 details
APOA1SERPINA1BioGRID24981860 details
APOA1HPXBioGRID24981860 details
APOA1ORM1BioGRID24981860 details
APOA1APOC2BioGRID24981860 details
APOA1DDX39BBioGRID32989256 details
APOA1TRIM37BioGRID33194618 details
APOA1HNF4AIntAct23628799 details