Entity Details

Primary name NLRP10
Entity type gene
Source Source Link

Details

PrimaryID338322
RefseqGeneNG_046899
SymbolNLRP10
NameNLR family pyrin domain containing 10
Chromosome11
Location11p15.4
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2003-02-28
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsNAL10_HUMAN

GO terms

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GOName
GO:0002250 adaptive immune response
GO:0002827 positive regulation of T-helper 1 type immune response
GO:0003924 GTPase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0006954 inflammatory response
GO:0016887 ATP hydrolysis activity
GO:0019897 extrinsic component of plasma membrane
GO:0032730 positive regulation of interleukin-1 alpha production
GO:0032755 positive regulation of interleukin-6 production
GO:0032757 positive regulation of interleukin-8 production
GO:0045087 innate immune response
GO:0050729 positive regulation of inflammatory response
GO:0050829 defense response to Gram-negative bacterium
GO:0050832 defense response to fungus
GO:1900426 positive regulation of defense response to bacterium
GO:2000318 positive regulation of T-helper 17 type immune response

Diseases

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Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
NLRP10ARBioGRID19762545 details
NLRP10EGFRBioGRID23956138 details
NLRP10TBC1D22BBioGRID, IntAct28514442 details
NLRP10H2BC18BioGRID, IntAct30021884 details
NLRP10BCAR1BioGRID33001583 details