Entity Details

Primary name MAP2K6
Entity type gene
Source Source Link

Details

PrimaryID5608
RefseqGeneNG_029437
SymbolMAP2K6
Namemitogen-activated protein kinase kinase 6
Chromosome17
Location17q24.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-14
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsMP2K6_HUMAN

GO terms

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GOName
GO:0000187 obsolete activation of MAPK activity
GO:0001649 osteoblast differentiation
GO:0002931 response to ischemia
GO:0004708 MAP kinase kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005524 ATP binding
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0006915 apoptotic process
GO:0006975 DNA damage induced protein phosphorylation
GO:0007165 signal transduction
GO:0019901 protein kinase binding
GO:0022602 ovulation cycle process
GO:0032308 positive regulation of prostaglandin secretion
GO:0042493 response to drug
GO:0042802 identical protein binding
GO:0043065 positive regulation of apoptotic process
GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process
GO:0060048 cardiac muscle contraction
GO:0060348 bone development
GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway
GO:0072709 cellular response to sorbitol
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:0120163 negative regulation of cold-induced thermogenesis
GO:1901796 regulation of signal transduction by p53 class mediator

Diseases

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Interactions

52 interactions

InteractorPartnerSourcesPublicationsLink
MAP2K6MAP3K4BioGRID, HPRD, IntAct12052864 15866172 16157600 17726008 25241761 9841871 details
MAP2K6MAPK14BioGRID, HPRD, MINT11279118 12697810 16342939 17255097 17255949 28205554 7750576 8622669 8626699 9808624 details
MAP2K6MLH1BioGRID, IntAct20706999 details
MAP2K6LRRK2BioGRID, IntAct19302196 20067578 details
MAP2K6TAOK2BioGRID, HPRD, IntAct10497253 11279118 25241761 details
MAP2K6MAP2K3BioGRID, IntAct25241761 26186194 28205554 28514442 details
MAP2K6PICK1BioGRID, IntAct32296183 details
MAP2K6MAP2K6BioGRID, DIP, HPRD19141286 28205554 8622669 8663074 details
MAP2K6NFE2L2IntAct32911434 details
MAP2K6WFS1IntAct32814053 details
MAP2K6MAP3K7BioGRID, HPRD10094049 10702308 10838074 11460167 12242293 12556533 12609980 12624112 14633987 15590691 15764709 16893890 17079228 17363905 17363973 17384642 19675569 20932476 23606331 23825189 26038599 details
MAP2K6MAP3K5BioGRID, HPRD11689443 12820963 15866172 16142216 20213747 25098452 details
MAP2K6TLR3BioGRID12609980 details
MAP2K6MAP2K4BioGRID15866172 details
MAP2K6MAPK12BioGRID, HPRD11062067 12761180 details
MAP2K6MAPKAPK2BioGRID17255097 details
MAP2K6MAPK1BioGRID10512765 details
MAP2K6FBXO7BioGRID27503909 details
MAP2K6MAP2K5BioGRID28205554 details
MAP2K6BRAFBioGRID28205554 details
MAP2K6AKT1BioGRID28205554 details
MAP2K6BECN1BioGRID28205554 details
MAP2K6CCND2BioGRID28205554 details
MAP2K6CDKN2BBioGRID28205554 details
MAP2K6EPHA2BioGRID28205554 details
MAP2K6FGFR4BioGRID28205554 details
MAP2K6GLIS2BioGRID28205554 details
MAP2K6HGFBioGRID28205554 details
MAP2K6HRASBioGRID28205554 details
MAP2K6RAF1BioGRID28205554 details
MAP2K6STK11BioGRID28205554 details
MAP2K6RASSF1BioGRID28205554 details
MAP2K6DCTN1HPRD15375157 details
MAP2K6PKN1BioGRID, HPRD, IntAct12761180 details
MAP2K6RELABioGRID, HPRD, IntAct16498455 25241761 details
MAP2K6SMAD7BioGRID, HPRD12589052 details
MAP2K6PLCB2BioGRID, HPRD12054652 details
MAP2K6PTENBioGRID15717329 details
MAP2K6FBXO31BioGRID24936062 details
MAP2K6RACK1BioGRID26038599 details
MAP2K6TRAF6BioGRID, HPRD16313339 26038599 details
MAP2K6APPBioGRID17719230 details
MAP2K6STAT4HPRD10961885 details
MAP2K6MAPK13HPRD9218798 details
MAP2K6MAP3K20HPRD11836244 details
MAP2K6GADD45ABioGRID, IntAct12052864 25241761 details
MAP2K6GADD45BIntAct12052864 details
MAP2K6GADD45GIntAct12052864 details
MAP2K6CST1BioGRID, IntAct28514442 details
MAP2K6ZG16BBioGRID26186194 details
MAP2K6DUSP4BioGRID27432908 details
MAP2K6PLEKHA4BioGRID31091453 details