Entity Details

Primary name ABCB5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ2M3G0
EntryNameABCB5_HUMAN
FullNameATP-binding cassette sub-family B member 5
TaxID9606
Evidenceevidence at protein level
Length1257
SequenceStatuscomplete
DateCreated2006-10-17
DateModified2021-06-02

Ontological Relatives

GenesABCB5

GO terms

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GOName
GO:0001654 eye development
GO:0005524 ATP binding
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0008559 ABC-type xenobiotic transporter activity
GO:0015562 efflux transmembrane transporter activity
GO:0016021 integral component of membrane
GO:0030154 cell differentiation
GO:0042391 regulation of membrane potential
GO:0042626 ATPase-coupled transmembrane transporter activity
GO:0055085 transmembrane transport

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR003439 ABC transporter-like, ATP-binding domainDomainDomain
IPR003593 AAA+ ATPase domainDomainDomain
IPR011527 ABC transporter type 1, transmembrane domainDomainDomain
IPR017871 ABC transporter-like, conserved siteSiteConserved site
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR036640 ABC transporter type 1, transmembrane domain superfamilyFamilyHomologous superfamily
IPR039421 Type 1 protein exporterFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB00254 DoxycyclineSwissprotsmall molecule
DB00598 LabetalolDrugbanksmall molecule
DB04851 BiricodarDrugbanksmall molecule
DB04948 LofexidineDrugbanksmall molecule
DB06263 AmrubicinDrugbanksmall molecule
DB08870 Brentuximab vedotinDrugbankbiotech
DB09183 DasabuvirDrugbanksmall molecule
DB11591 BilastineDrugbanksmall molecule
DB11641 VinflunineDrugbanksmall molecule
DB11691 NaldemedineDrugbanksmall molecule
DB11943 DelafloxacinDrugbanksmall molecule
DB12010 FostamatinibDrugbanksmall molecule
DB12267 BrigatinibDrugbanksmall molecule
DB13997 Baloxavir marboxilDrugbanksmall molecule
DB14067 DofequidarDrugbanksmall molecule