Entity Details

Primary name S22A6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ4U2R8
EntryNameS22A6_HUMAN
FullNameSolute carrier family 22 member 6
TaxID9606
Evidenceevidence at protein level
Length563
SequenceStatuscomplete
DateCreated2008-03-18
DateModified2021-06-02

Ontological Relatives

GenesSLC22A6

GO terms

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GOName
GO:0005452 inorganic anion exchanger activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005901 caveola
GO:0008514 organic anion transmembrane transporter activity
GO:0015301 anion:anion antiporter activity
GO:0015347 sodium-independent organic anion transmembrane transporter activity
GO:0015711 organic anion transport
GO:0015742 alpha-ketoglutarate transport
GO:0016323 basolateral plasma membrane
GO:0031404 chloride ion binding
GO:0031427 response to methotrexate
GO:0032991 protein-containing complex
GO:0042802 identical protein binding
GO:0043252 sodium-independent organic anion transport
GO:0070062 extracellular exosome
GO:0097254 renal tubular secretion

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR004749 Organic cation transport protein/SVOPFamilyFamily
IPR005828 Major facilitator, sugar transporter-likeFamilyFamily
IPR020846 Major facilitator superfamily domainDomainDomain
IPR036259 MFS transporter superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00091 CyclosporineDrugbanksmall molecule
DB00140 RiboflavinDrugbanksmall molecule
DB00155 CitrullineDrugbanksmall molecule
DB00158 Folic acidDrugbanksmall molecule
DB00168 AspartameDrugbanksmall molecule
DB00175 PravastatinDrugbanksmall molecule
DB00229 CefotiamDrugbanksmall molecule
DB00254 DoxycyclineSwissprotsmall molecule
DB00286 Conjugated estrogensDrugbanksmall molecule
DB00300 Tenofovir disoproxilDrugbanksmall molecule
DB00311 EthoxzolamideDrugbanksmall molecule
DB00313 Valproic acidDrugbanksmall molecule
DB00319 PiperacillinDrugbanksmall molecule
DB00328 IndomethacinDrugbanksmall molecule
DB00345 Aminohippuric acidSwissprotsmall molecule
DB00365 GrepafloxacinDrugbanksmall molecule
DB00369 CidofovirDrugbanksmall molecule
DB00432 TrifluridineDrugbanksmall molecule
DB00438 CeftazidimeDrugbanksmall molecule
DB00446 ChloramphenicolDrugbanksmall molecule
DB00456 CefalotinDrugbanksmall molecule
DB00493 CefotaximeDrugbanksmall molecule
DB00495 ZidovudineDrugbanksmall molecule
DB00500 TolmetinDrugbanksmall molecule
DB00501 CimetidineDrugbanksmall molecule
DB00520 CaspofunginDrugbanksmall molecule
DB00529 FoscarnetDrugbanksmall molecule
DB00535 CefdinirDrugbanksmall molecule
DB00554 PiroxicamDrugbanksmall molecule
DB00563 MethotrexateDrugbanksmall molecule
DB00567 CephalexinDrugbanksmall molecule
DB00577 ValaciclovirDrugbanksmall molecule
DB00578 CarbenicillinDrugbanksmall molecule
DB00584 EnalaprilDrugbanksmall molecule
DB00586 DiclofenacDrugbanksmall molecule
DB00595 OxytetracyclineDrugbanksmall molecule
DB00605 SulindacDrugbanksmall molecule
DB00606 CyclothiazideDrugbanksmall molecule
DB00607 NafcillinDrugbanksmall molecule
DB00649 StavudineDrugbanksmall molecule
DB00654 LatanoprostDrugbanksmall molecule
DB00672 ChlorpropamideDrugbanksmall molecule
DB00678 LosartanDrugbanksmall molecule
DB00693 FluoresceinDrugbanksmall molecule
DB00695 FurosemideDrugbanksmall molecule
DB00703 MethazolamideDrugbanksmall molecule
DB00709 LamivudineDrugbanksmall molecule
DB00712 FlurbiprofenDrugbanksmall molecule
DB00718 Adefovir dipivoxilDrugbanksmall molecule
DB00731 NateglinideDrugbanksmall molecule
DB00749 EtodolacDrugbanksmall molecule
DB00759 TetracyclineDrugbanksmall molecule
DB00770 AlprostadilDrugbanksmall molecule
DB00774 HydroflumethiazideDrugbanksmall molecule
DB00779 Nalidixic acidSwissprotsmall molecule
DB00787 AcyclovirDrugbanksmall molecule
DB00788 NaproxenDrugbanksmall molecule
DB00798 GentamicinDrugbanksmall molecule
DB00812 PhenylbutazoneDrugbanksmall molecule
DB00819 AcetazolamideDrugbanksmall molecule
DB00821 CarprofenDrugbanksmall molecule
DB00827 CinoxacinDrugbanksmall molecule
DB00861 DiflunisalDrugbanksmall molecule
DB00880 ChlorothiazideDrugbanksmall molecule
DB00887 BumetanideDrugbanksmall molecule
DB00900 DidanosineDrugbanksmall molecule
DB00903 Etacrynic acidDrugbanksmall molecule
DB00917 DinoprostoneDrugbanksmall molecule
DB00927 FamotidineDrugbanksmall molecule
DB00936 Salicylic acidDrugbanksmall molecule
DB00939 Meclofenamic acidDrugbanksmall molecule
DB00943 ZalcitabineDrugbanksmall molecule
DB00945 Acetylsalicylic acidDrugbanksmall molecule
DB00999 HydrochlorothiazideDrugbanksmall molecule
DB01004 GanciclovirDrugbanksmall molecule
DB01009 KetoprofenDrugbanksmall molecule
DB01016 GlyburideDrugbanksmall molecule
DB01017 MinocyclineDrugbanksmall molecule
DB01032 ProbenecidDrugbanksmall molecule
DB01045 RifampicinDrugbanksmall molecule
DB01050 IbuprofenDrugbanksmall molecule
DB01051 NovobiocinDrugbanksmall molecule
DB01053 BenzylpenicillinDrugbanksmall molecule
DB01059 NorfloxacinDrugbanksmall molecule
DB01060 AmoxicillinDrugbanksmall molecule
DB01082 StreptomycinDrugbanksmall molecule
DB01124 TolbutamideDrugbanksmall molecule
DB01140 CefadroxilDrugbanksmall molecule
DB01147 CloxacillinDrugbanksmall molecule
DB01160 Dinoprost tromethamineDrugbanksmall molecule
DB01165 OfloxacinDrugbanksmall molecule
DB01197 CaptoprilDrugbanksmall molecule
DB01212 CeftriaxoneDrugbanksmall molecule
DB01237 BromodiphenhydramineDrugbanksmall molecule
DB01324 PolythiazideDrugbanksmall molecule
DB01326 CefamandoleDrugbanksmall molecule
DB01327 CefazolinDrugbanksmall molecule
DB01329 CefoperazoneDrugbanksmall molecule
DB01332 CeftizoximeDrugbanksmall molecule
DB01333 CefradineDrugbanksmall molecule
DB01414 CefacetrileDrugbanksmall molecule
DB01415 CeftibutenDrugbanksmall molecule
DB01424 AminophenazoneSwissprotsmall molecule
DB01435 AntipyrineDrugbanksmall molecule
DB01597 CilastatinDrugbanksmall molecule
DB01606 TazobactamDrugbanksmall molecule
DB01685 TopiroxostatDrugbanksmall molecule
DB02266 Flufenamic acidDrugbanksmall molecule
DB02315 Cyclic GMPDrugbanksmall molecule
DB02527 Cyclic adenosine monophosphateDrugbanksmall molecule
DB03553 Glutaric AcidDrugbanksmall molecule
DB03585 OxyphenbutazoneDrugbanksmall molecule
DB03783 PhenacetinDrugbanksmall molecule
DB04133 Degraded CephaloridineDrugbanksmall molecule
DB04348 Taurocholic acidDrugbanksmall molecule
DB04519 Caprylic acidDrugbanksmall molecule
DB05016 AtalurenSwissprotsmall molecule
DB06151 AcetylcysteineDrugbanksmall molecule
DB08843 GS 0573Swissprotsmall molecule
DB08844 Uric acidSwissprotsmall molecule
DB08846 Ellagic acidDrugbanksmall molecule
DB08912 DabrafenibDrugbanksmall molecule
DB08930 DolutegravirDrugbanksmall molecule
DB09008 CefaloridineSwissprotsmall molecule
DB09078 LenvatinibDrugbanksmall molecule
DB09213 DexibuprofenDrugbanksmall molecule
DB09298 SilibininSwissprotsmall molecule
DB09299 Tenofovir alafenamideDrugbanksmall molecule
DB11644 TafamidisDrugbanksmall molecule
DB11751 CabotegravirSwissprotsmall molecule
DB11757 IstradefyllineDrugbanksmall molecule
DB11817 BaricitinibDrugbanksmall molecule
DB11837 OsilodrostatDrugbanksmall molecule
DB12243 EdaravoneSwissprotsmall molecule
DB12332 RucaparibDrugbanksmall molecule
DB12466 FavipiravirDrugbanksmall molecule
DB13874 EnasidenibDrugbanksmall molecule
DB14126 TenofovirDrugbanksmall molecule
DB15328 UbrogepantDrugbanksmall molecule
DB15822 PralsetinibDrugbanksmall molecule

Interactions

4 interactions