Entity Details

Primary name NUCL_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP19338
EntryNameNUCL_HUMAN
FullNameNucleolin
TaxID9606
Evidenceevidence at protein level
Length710
SequenceStatuscomplete
DateCreated1990-11-01
DateModified2021-06-02

Ontological Relatives

GenesNCL

GO terms

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GOName
GO:0001525 angiogenesis
GO:0003723 RNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005681 spliceosomal complex
GO:0005694 chromosome
GO:0005730 nucleolus
GO:0005938 cell cortex
GO:0008022 protein C-terminus binding
GO:0016020 membrane
GO:0017148 negative regulation of translation
GO:0036464 cytoplasmic ribonucleoprotein granule
GO:0042162 telomeric DNA binding
GO:0042802 identical protein binding
GO:0044547 DNA topoisomerase binding
GO:0048026 positive regulation of mRNA splicing, via spliceosome
GO:0048027 mRNA 5'-UTR binding
GO:0070062 extracellular exosome
GO:1901838 positive regulation of transcription of nucleolar large rRNA by RNA polymerase I
GO:1990904 ribonucleoprotein complex

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000504 RNA recognition motif domainDomainDomain
IPR003954 RNA recognition motif domain, eukaryoteDomainDomain
IPR012677 Nucleotide-binding alpha-beta plait domain superfamilyFamilyHomologous superfamily
IPR034230 Nucleolin, RNA recognition motif 1DomainDomain
IPR034233 Nucleolin, RNA recognition motif 2DomainDomain
IPR034234 Nucleolin, RNA recognition motif 3DomainDomain
IPR034235 Nucleolin, RNA recognition motif 4DomainDomain
IPR035979 RNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

149 interactions

InteractorPartnerSourcesPublicationsLink
NUCL_HUMANGRB2_HUMANBioGRID, IntAct12577067 20936779 details
NUCL_HUMANTOP1_HUMANBioGRID, HPRD, IntAct, MINT10967121 15848144 8567649 9512561 details
NUCL_HUMANHMGA1_HUMANBioGRID, IntAct18850631 details
NUCL_HUMANMDM2_HUMANBioGRID, IntAct, MINT16751805 20195357 22103682 24147044 30948704 details
NUCL_HUMANETS1_HUMANBioGRID, IntAct20195357 details
NUCL_HUMANESR1_HUMANBioGRID, IntAct20348541 21182205 details
NUCL_HUMANTRFL_HUMANMINT21575138 details
NUCL_HUMANNUCL_HUMANBioGRID, MINT21575138 25313645 details
NUCL_HUMANP53_HUMANBioGRID, HPRD, MINT12138209 22103682 26238070 32807901 details
NUCL_HUMANDUX4_HUMANBioGRID, IntAct26816005 details
NUCL_HUMANCSK21_HUMANBioGRID, HPRD, IntAct22113938 26344197 8663258 details
NUCL_HUMANH31T_HUMANBioGRID, IntAct20850016 30021884 details
NUCL_HUMANNPM_HUMANBioGRID, HPRD, IntAct10503877 16648475 20431927 21048921 22362753 22939629 28514442 8620867 details
NUCL_HUMANCSK22_HUMANBioGRID, HPRD8663258 details
NUCL_HUMANMYBA_HUMANBioGRID, HPRD10660576 details
NUCL_HUMANTERT_HUMANBioGRID, HPRD15371412 details
NUCL_HUMANCD3E_HUMANBioGRID, HPRD11115514 details
NUCL_HUMANS10AB_HUMANBioGRID, HPRD14623863 details
NUCL_HUMANGCR_HUMANBioGRID, HPRD11162542 8530516 details
NUCL_HUMANTERF2_HUMANbhf-ucl, BioGRID21044950 details
NUCL_HUMANH2A2C_HUMANBioGRID16601700 details
NUCL_HUMANH2B2E_HUMANBioGRID16601700 details
NUCL_HUMANTTP_HUMANBioGRID20221403 details
NUCL_HUMANKPCZ_HUMANBioGRID, HPRD9388266 details
NUCL_HUMANMK_HUMANBioGRID, HPRD12147681 details
NUCL_HUMANGZF1_HUMANBioGRID17674968 details
NUCL_HUMANADAP1_HUMANBioGRID, HPRD12565890 18298663 details
NUCL_HUMANRPA34_HUMANBioGRID23145133 34079125 details
NUCL_HUMANARF_HUMANBioGRID, HPRD14636574 16582619 details
NUCL_HUMANERG_HUMANBioGRID24591637 details
NUCL_HUMANMDC1_HUMANBioGRID23145133 details
NUCL_HUMANH12_HUMANBioGRID18258596 details
NUCL_HUMANADAP2_HUMANBioGRID18298663 details
NUCL_HUMANPIDD1_HUMANBioGRID16982033 details
NUCL_HUMANANM5_HUMANBioGRID17974993 21081503 details
NUCL_HUMANCDK1_HUMANBioGRID24530506 details
NUCL_HUMANRAD51_HUMANBioGRID16600179 details
NUCL_HUMANSREK1_HUMANBioGRID, HPRD14559993 details
NUCL_HUMANH2AX_HUMANBioGRID23145133 details
NUCL_HUMANXRCC6_HUMANBioGRID23145133 30585729 details
NUCL_HUMANNBN_HUMANBioGRID23145133 details
NUCL_HUMAN1433T_HUMANBioGRID15161933 details
NUCL_HUMANVHL_HUMANBioGRID22234250 details
NUCL_HUMANSRPK2_HUMANBioGRID26167880 details
NUCL_HUMANRIOK1_HUMANBioGRID21081503 details
NUCL_HUMANCLK1_HUMANBioGRID26167880 details
NUCL_HUMANOGT1_HUMANBioGRID32994395 details
NUCL_HUMANZFP41_HUMANBioGRID32296183 details
NUCL_HUMANSUMO2_HUMANBioGRID32786267 details
NUCL_HUMANSTAU1_HUMANBioGRID, HPRD, IntAct15121898 15303970 23125841 29395067 30948266 details
NUCL_HUMANIKBB_HUMANIntAct14743216 details
NUCL_HUMANM3K14_HUMANIntAct14743216 details
NUCL_HUMANHCK_HUMANMINT12029088 details
NUCL_HUMANM3K1_HUMANIntAct14743216 details
NUCL_HUMAN1433Z_HUMANMINT15161933 details
NUCL_HUMANPA2G4_HUMANBioGRID, UniProt15064750 19037095 19946338 details
NUCL_HUMANNFKB2_HUMANIntAct14743216 details
NUCL_HUMANANR28_HUMANIntAct17928403 details
NUCL_HUMANNECD_HUMANBioGRID, IntAct, MINT20195357 32529326 details
NUCL_HUMANTF65_HUMANIntAct14743216 details
NUCL_HUMANARRB2_HUMANBioGRID, IntAct17620599 details
NUCL_HUMANKAP0_HUMANIntAct20195357 details
NUCL_HUMANCASP8_HUMANMINT17290218 details
NUCL_HUMANPAX8_HUMANIntAct20195357 details
NUCL_HUMANPP1B_HUMANBioGRID, MINT12185196 details
NUCL_HUMANARRB1_HUMANBioGRID, IntAct17620599 details
NUCL_HUMANNXF1_HUMANBioGRID, UniProt18596238 27049334 details
NUCL_HUMANPHS_HUMANIntAct20195357 details
NUCL_HUMANPO5F1_HUMANBioGRID, IntAct21048921 21151833 details
NUCL_HUMANROCK2_HUMANMINT21281639 details
NUCL_HUMANMYH9_HUMANIntAct16403913 details
NUCL_HUMANEGFR_HUMANBioGRID, IntAct24780295 25261371 28065597 details
NUCL_HUMANNUP62_HUMANBioGRID, DIP14973189 18292223 details
NUCL_HUMANRHOA_HUMANMINT21281639 details
NUCL_HUMANAPTX_HUMANIntAct15044383 details
NUCL_HUMANRRP1B_HUMANBioGRID, IntAct19710015 20926688 27049334 details
NUCL_HUMANSRSF2_HUMANMINT23353999 details
NUCL_HUMANRB_HUMANIntAct20195357 details
NUCL_HUMANPAIRB_HUMANMINT24205981 details
NUCL_HUMANFOS_HUMANIntAct20195357 details
NUCL_HUMANBIG1_HUMANBioGRID, DIP14973189 18292223 details
NUCL_HUMANRAC3_HUMANIntAct20195357 details
NUCL_HUMANMYB_HUMANBioGRID, HPRD10660576 details
NUCL_HUMANLA_HUMANBioGRID, DIP, HPRD12096904 18292223 details
NUCL_HUMANSWP70_HUMANBioGRID9642267 details
NUCL_HUMANNFE4_HUMANBioGRID, DIP19234465 22689669 details
NUCL_HUMANMBB1A_HUMANBioGRID21386990 27049334 details
NUCL_HUMANF90AR_HUMANIntAct30021884 details
NUCL_HUMANNOP56_HUMANBioGRID12777385 34079125 details
NUCL_HUMANSP1_HUMANBioGRID14623863 details
NUCL_HUMANNPM3_HUMANBioGRID22362753 22863883 26344197 details
NUCL_HUMANCYFP1_HUMANBioGRID11438699 details
NUCL_HUMANFMR1_HUMANBioGRID, HPRD10567518 details
NUCL_HUMANICAL_HUMANIntAct30021884 details
NUCL_HUMANNFX1_HUMANBioGRID17267499 31059266 details
NUCL_HUMANMGMT_HUMANBioGRID16226712 details
NUCL_HUMANEPHA4_HUMANIntAct31413325 details
NUCL_HUMANITA4_HUMANBioGRID22623428 details
NUCL_HUMANRECQ5_HUMANBioGRID19270065 details
NUCL_HUMANSIR7_HUMANBioGRID22586326 26867678 details
NUCL_HUMANP85A_HUMANBioGRID16571724 details
NUCL_HUMANNSUN2_HUMANBioGRID17215513 details
NUCL_HUMANCDN2A_HUMANBioGRID14636574 details
NUCL_HUMANU2AF2_HUMANBioGRID26641092 27049334 details
NUCL_HUMANH33_HUMANBioGRID17403666 details
NUCL_HUMANEXOSX_HUMANBioGRID27049334 details
NUCL_HUMANDGCR8_HUMANBioGRID17765891 details
NUCL_HUMANZN689_HUMANBioGRID, HPRD16568080 details
NUCL_HUMANUIF_HUMANBioGRID19836239 details
NUCL_HUMANTHOC4_HUMANBioGRID27049334 details
NUCL_HUMANCD81_HUMANBioGRID23463506 details
NUCL_HUMANDHX9_HUMANBioGRID22751105 27049334 details
NUCL_HUMANRN168_HUMANBioGRID27558965 details
NUCL_HUMANRN146_HUMANBioGRID21825151 details
NUCL_HUMANHNRPD_HUMANBioGRID16571724 26318153 details
NUCL_HUMANGAN_HUMANBioGRID26460568 details
NUCL_HUMANMYCN_HUMANBioGRID26528759 details
NUCL_HUMANPABP1_HUMANBioGRID20221403 details
NUCL_HUMANUBP7_HUMANBioGRID25695607 26238070 details
NUCL_HUMANREST_HUMANBioGRID27976729 details
NUCL_HUMANMAGD2_HUMANBioGRID26705694 details
NUCL_HUMANPTPRZ_HUMANBioGRID23161541 details
NUCL_HUMANSOX2_HUMANBioGRID21280222 details
NUCL_HUMANVRK1_HUMANBioGRID28927264 details
NUCL_HUMANZCCHV_HUMANBioGRID27049334 details
NUCL_HUMANCMTR1_HUMANBioGRID30320910 details
NUCL_HUMANVRK3_HUMANBioGRID28927264 details
NUCL_HUMANUBE2S_HUMANBioGRID27593939 details
NUCL_HUMANECT2_HUMANBioGRID31586073 32929379 details
NUCL_HUMANIGSF8_HUMANBioGRID23463506 details
NUCL_HUMANARAF_HUMANBioGRID29777862 details
NUCL_HUMANMEP50_HUMANBioGRID21081503 details
NUCL_HUMANERCC8_HUMANBioGRID31970402 details
NUCL_HUMANICAM1_HUMANBioGRID23463506 details
NUCL_HUMANERCC6_HUMANBioGRID31970402 details
NUCL_HUMANAPEX1_HUMANBioGRID28986522 details
NUCL_HUMANPRGC1_HUMANHPRD10983978 details
NUCL_HUMANZBTB1_HUMANBioGRID24657165 details
NUCL_HUMANPARP1_HUMANBioGRID, HPRD34079125 9642267 details
NUCL_HUMANING4_HUMANBioGRID31754246 details
NUCL_HUMANPPM1D_HUMANHPRD12185196 details
NUCL_HUMANEIF3H_HUMANBioGRID32269044 details
NUCL_HUMANIRF2_HUMANBioGRID16582966 details
NUCL_HUMANCTCF_HUMANBioGRID19450526 details
NUCL_HUMANDDX24_HUMANBioGRID24980433 details
NUCL_HUMANITAV_HUMANBioGRID23161541 details
NUCL_HUMANMSH6_HUMANBioGRID27049334 details
NUCL_HUMANERPG3_HUMANBioGRID31970402 details
NUCL_HUMANGRAA_HUMANHPRD1860869 details