Entity Details

Primary name RHG01_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ07960
EntryNameRHG01_HUMAN
FullNameRho GTPase-activating protein 1
TaxID9606
Evidenceevidence at protein level
Length439
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesARHGAP1

GO terms

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GOName
GO:0005096 GTPase activator activity
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0007264 small GTPase mediated signal transduction
GO:0007266 Rho protein signal transduction
GO:0010008 endosome membrane
GO:0016197 endosomal transport
GO:0017124 SH3 domain binding
GO:0031267 small GTPase binding
GO:0033572 transferrin transport
GO:0045296 cadherin binding
GO:0048471 perinuclear region of cytoplasm
GO:0051056 regulation of small GTPase mediated signal transduction
GO:0070062 extracellular exosome
GO:2001136 negative regulation of endocytic recycling

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000198 Rho GTPase-activating protein domainDomainDomain
IPR001251 CRAL-TRIO lipid binding domainDomainDomain
IPR008936 Rho GTPase activation proteinFamilyHomologous superfamily
IPR036865 CRAL-TRIO lipid binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

26 interactions

InteractorPartnerSourcesPublicationsLink
RHG01_HUMANCDC42_HUMANBioGRID, DIP, HPRD, IntAct10551883 10684602 14749388 9262406 9268338 9338791 9407060 9427749 9535855 9846874 details
RHG01_HUMANRHOC_HUMANBioGRID, HPRD, IntAct16189514 details
RHG01_HUMANRHOA_HUMANBioGRID, HPRD, IntAct11927263 14749388 16189514 20660160 31467278 9407060 9535855 9548756 details
RHG01_HUMANATRAP_HUMANBioGRID, MINT21516116 details
RHG01_HUMANCHK2_HUMANBioGRID, IntAct21988832 details
RHG01_HUMANMTR1B_HUMANBioGRID, IntAct26514267 details
RHG01_HUMANSH3G1_HUMANBioGRID, IntAct32296183 details
RHG01_HUMANBNIP2_HUMANBioGRID, HPRD, IntAct10551883 10954711 29997244 details
RHG01_HUMANBNIPL_HUMANBioGRID, HPRD12901880 details
RHG01_HUMANRHG01_HUMANBioGRID, HPRD10954711 11741952 details
RHG01_HUMANSRC_HUMANBioGRID, HPRD8253717 details
RHG01_HUMANP85A_HUMANBioGRID, HPRD8253717 details
RHG01_HUMANRAC1_HUMANBioGRID14749388 9535855 details
RHG01_HUMANOGT1_HUMANBioGRID32994395 details
RHG01_HUMANTBA4A_HUMANHPRD14697242 details
RHG01_HUMANWASP_HUMANHPRD8805223 details
RHG01_HUMANSMRD3_HUMANHPRD14697242 details
RHG01_HUMANE41L1_HUMANHPRD14697242 details
RHG01_HUMANTAXB1_HUMANHPRD14697242 details
RHG01_HUMANKIF1B_HUMANHPRD14697242 details
RHG01_HUMANHS90B_HUMANHPRD14697242 details
RHG01_HUMANHMDH_HUMANHPRD14697242 details
RHG01_HUMANITPR1_HUMANHPRD14697242 details
RHG01_HUMANST7_HUMANBioGRID29395067 details
RHG01_HUMANPTN11_HUMANHPRD15169898 15588985 details
RHG01_HUMANRASA1_HUMANHPRD9034330 details