Entity Details

Primary name NADC_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ15274
EntryNameNADC_HUMAN
FullNameNicotinate-nucleotide pyrophosphorylase [carboxylating]
TaxID9606
Evidenceevidence at protein level
Length297
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesQPRT

GO terms

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GOName
GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0009435 NAD biosynthetic process
GO:0019674 NAD metabolic process
GO:0034213 quinolinate catabolic process
GO:0042802 identical protein binding
GO:0070062 extracellular exosome
GO:1902494 catalytic complex

Subcellular Location

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Domains

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DomainNameCategoryType
IPR002638 Quinolinate phosphoribosyl transferase, C-terminalDomainDomain
IPR004393 Nicotinate-nucleotide pyrophosphorylaseFamilyFamily
IPR013785 Aldolase-type TIM barrelFamilyHomologous superfamily
IPR022412 Quinolinate phosphoribosyl transferase, N-terminalDomainDomain
IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModDFamilyFamily
IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminalFamilyHomologous superfamily
IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00627 NiacinDrugbanksmall molecule