Entity Details

Primary name GPX2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP18283
EntryNameGPX2_HUMAN
FullNameGlutathione peroxidase 2
TaxID9606
Evidenceevidence at protein level
Length190
SequenceStatuscomplete
DateCreated1990-11-01
DateModified2021-06-02

Ontological Relatives

GenesGPX2

GO terms

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GOName
GO:0004601 peroxidase activity
GO:0004602 glutathione peroxidase activity
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0009055 electron transfer activity
GO:0034599 cellular response to oxidative stress

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000889 Glutathione peroxidaseFamilyFamily
IPR029759 Glutathione peroxidase active siteSiteActive site
IPR029760 Glutathione peroxidase conserved siteSiteConserved site
IPR036249 Thioredoxin-like superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00143 GlutathioneDrugbanksmall molecule
DB03310 Glutathione disulfideDrugbanksmall molecule

Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
GPX2_HUMANMYC_HUMANBioGRID, IntAct21988832 details
GPX2_HUMANPSB2_HUMANBioGRID, IntAct21988832 details
GPX2_HUMANP53_HUMANBioGRID, IntAct21988832 details
GPX2_HUMANGPX2_HUMANHPRD8428933 details