Entity Details

Primary name TMC8
Entity type gene
Source Source Link

Details

PrimaryID147138
RefseqGeneNG_007881
SymbolTMC8
Nametransmembrane channel like 8
Chromosome17
Location17q25.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2002-01-22
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsTMC8_HUMAN

GO terms

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GOName
GO:0001558 regulation of cell growth
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0005887 integral component of plasma membrane
GO:0008381 mechanosensitive ion channel activity
GO:0031333 negative regulation of protein-containing complex assembly
GO:0031965 nuclear membrane
GO:0032091 negative regulation of protein binding
GO:0043120 tumor necrosis factor binding
GO:0055069 zinc ion homeostasis
GO:0070062 extracellular exosome
GO:0140311 protein sequestering activity
GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors

Diseases

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Interactions

6 interactions

InteractorPartnerSourcesPublicationsLink
TMC8TRADDBioGRID23429285 details
TMC8TRAF1BioGRID24586810 details
TMC8TRAF2BioGRID24586810 details
TMC8TNFRSF1ABioGRID23429285 details
TMC8H1-4BioGRID, IntAct30021884 details
TMC8DDX58BioGRID32513696 details