Entity Details

Primary name PHC3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8NDX5
EntryNamePHC3_HUMAN
FullNamePolyhomeotic-like protein 3
TaxID9606
Evidenceevidence at protein level
Length983
SequenceStatuscomplete
DateCreated2005-12-20
DateModified2021-06-02

Ontological Relatives

GenesPHC3

GO terms

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GOName
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0007275 multicellular organism development
GO:0008270 zinc ion binding
GO:0031519 PcG protein complex
GO:0035102 PRC1 complex
GO:0042393 histone binding
GO:0045892 negative regulation of transcription, DNA-templated
GO:0070317 negative regulation of G0 to G1 transition

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001660 Sterile alpha motif domainDomainDomain
IPR012313 Zinc finger, FCS-typeDomainDomain
IPR013761 Sterile alpha motif/pointed domain superfamilyFamilyHomologous superfamily
IPR038603 FCS-type zinc finger superfamilyFamilyHomologous superfamily

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
PHC3_HUMANOGT1_HUMANBioGRID, IntAct25416956 details
PHC3_HUMANAGR2_HUMANBioGRID, IntAct32296183 details
PHC3_HUMANH31T_HUMANBioGRID20850016 details
PHC3_HUMANHYPK_HUMANBioGRID32296183 details