Entity Details

Primary name GATA6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ92908
EntryNameGATA6_HUMAN
FullNameTranscription factor GATA-6
TaxID9606
Evidenceevidence at protein level
Length595
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesGATA6

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001701 in utero embryonic development
GO:0001889 liver development
GO:0001949 sebaceous gland cell differentiation
GO:0002759 regulation of antimicrobial humoral response
GO:0003148 outflow tract septum morphogenesis
GO:0003162 atrioventricular node development
GO:0003309 type B pancreatic cell differentiation
GO:0003310 pancreatic A cell differentiation
GO:0003682 chromatin binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006644 phospholipid metabolic process
GO:0007493 endodermal cell fate determination
GO:0007596 blood coagulation
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0008584 male gonad development
GO:0014898 cardiac muscle hypertrophy in response to stress
GO:0019901 protein kinase binding
GO:0030855 epithelial cell differentiation
GO:0031965 nuclear membrane
GO:0032526 response to retinoic acid
GO:0032911 negative regulation of transforming growth factor beta1 production
GO:0032912 negative regulation of transforming growth factor beta2 production
GO:0035239 tube morphogenesis
GO:0036302 atrioventricular canal development
GO:0042493 response to drug
GO:0043066 negative regulation of apoptotic process
GO:0043627 response to estrogen
GO:0044267 cellular protein metabolic process
GO:0045165 cell fate commitment
GO:0045766 positive regulation of angiogenesis
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048645 animal organ formation
GO:0051145 smooth muscle cell differentiation
GO:0051891 positive regulation of cardioblast differentiation
GO:0055007 cardiac muscle cell differentiation
GO:0060045 positive regulation of cardiac muscle cell proliferation
GO:0060430 lung saccule development
GO:0060486 club cell differentiation
GO:0060510 type II pneumocyte differentiation
GO:0060575 intestinal epithelial cell differentiation
GO:0060947 cardiac vascular smooth muscle cell differentiation
GO:0070848 response to growth factor
GO:0071371 cellular response to gonadotropin stimulus
GO:0071456 cellular response to hypoxia
GO:0071773 cellular response to BMP stimulus
GO:0098773 skin epidermis development
GO:0110024 positive regulation of cardiac muscle myoblast proliferation
GO:1901390 positive regulation of transforming growth factor beta activation
GO:1904003 negative regulation of sebum secreting cell proliferation
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000679 Zinc finger, GATA-typeDomainDomain
IPR008013 GATA-type transcription activator, N-terminalDomainDomain
IPR013088 Zinc finger, NHR/GATA-typeFamilyHomologous superfamily
IPR028437 Transcription factor GATA-6FamilyFamily
IPR039355 Transcription factor GATAFamilyFamily

Diseases

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