Entity Details

Primary name SYTL4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96C24
EntryNameSYTL4_HUMAN
FullNameSynaptotagmin-like protein 4
TaxID9606
Evidenceevidence at protein level
Length671
SequenceStatuscomplete
DateCreated2003-07-25
DateModified2021-06-02

Ontological Relatives

GenesSYTL4

GO terms

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GOName
GO:0001778 plasma membrane repair
GO:0002576 platelet degranulation
GO:0005543 phospholipid binding
GO:0005768 endosome
GO:0005886 plasma membrane
GO:0006886 intracellular protein transport
GO:0006887 exocytosis
GO:0019898 extrinsic component of membrane
GO:0030658 transport vesicle membrane
GO:0031092 platelet alpha granule membrane
GO:0031267 small GTPase binding
GO:0032418 lysosome localization
GO:0042043 neurexin family protein binding
GO:0045921 positive regulation of exocytosis
GO:0046676 negative regulation of insulin secretion
GO:0046872 metal ion binding
GO:0050714 positive regulation of protein secretion
GO:0070382 exocytic vesicle
GO:0071985 multivesicular body sorting pathway
GO:1905684 regulation of plasma membrane repair

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasmic vesicle
Membrane

Domains

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DomainNameCategoryType
IPR000008 C2 domainDomainDomain
IPR001565 SynaptotagminDomainDomain
IPR010911 Rab-binding domainDomainDomain
IPR011011 Zinc finger, FYVE/PHD-typeFamilyHomologous superfamily
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR028694 Synaptotagmin-like protein 4FamilyFamily
IPR035892 C2 domain superfamilyFamilyHomologous superfamily
IPR037303 Synaptotagmin-like protein 4/5, C2A domainDomainDomain
IPR041282 FYVE-type zinc fingerDomainDomain
IPR043567 Synaptotagmin-like 1-5, C2B domainDomainDomain
IPR044134 Synaptotagmin-like protein 4 , FYVE-related domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00071 Insulin porkDrugbankbiotech

Interactions

35 interactions

InteractorPartnerSourcesPublicationsLink
SYTL4_HUMANCC85B_HUMANBioGRID, HPRD, IntAct16189514 details
SYTL4_HUMANZBT7B_HUMANBioGRID, IntAct25416956 details
SYTL4_HUMANFXR2_HUMANBioGRID, IntAct25416956 32296183 details
SYTL4_HUMANCEP70_HUMANBioGRID, IntAct25416956 31515488 details
SYTL4_HUMANHM20A_HUMANBioGRID, IntAct25416956 31515488 32296183 details
SYTL4_HUMANRAB8A_HUMANBioGRID, HPRD, IntAct, UniProt11773082 12176990 12590134 23140275 24700782 26553929 26824392 29125462 details
SYTL4_HUMANDVL3_HUMANBioGRID, IntAct32296183 details
SYTL4_HUMANROP1A_HUMANBioGRID, IntAct32296183 details
SYTL4_HUMANKIFC3_HUMANBioGRID, IntAct32296183 details
SYTL4_HUMANTRI41_HUMANBioGRID, IntAct32296183 details
SYTL4_HUMANTRI37_HUMANBioGRID, IntAct32296183 details
SYTL4_HUMANZBTB9_HUMANBioGRID, IntAct32296183 details
SYTL4_HUMANRB27A_HUMANBioGRID, HPRD, IntAct11773082 11865063 12101244 12176990 12590134 24700782 32296183 details
SYTL4_HUMANRAB3D_HUMANBioGRID, IntAct32296183 details
SYTL4_HUMANKAP1_HUMANBioGRID, IntAct32296183 details
SYTL4_HUMANZRAN1_HUMANBioGRID, IntAct32296183 details
SYTL4_HUMANOSBL3_HUMANBioGRID, IntAct32296183 details
SYTL4_HUMANLZTS1_HUMANBioGRID, IntAct32296183 details
SYTL4_HUMANTBCD1_HUMANBioGRID, IntAct32296183 details
SYTL4_HUMANRBTN1_HUMANBioGRID, IntAct32296183 details
SYTL4_HUMANSTXB1_HUMANBioGRID, HPRD, IntAct12590134 15563604 24700782 32296183 details
SYTL4_HUMANSPXN2_HUMANBioGRID, IntAct32296183 details
SYTL4_HUMANRB27B_HUMANBioGRID, HPRD, IntAct11956164 28514442 details
SYTL4_HUMANRAB3A_HUMANBioGRID, HPRD, IntAct11773082 11865063 12176990 12590134 26186194 28514442 details
SYTL4_HUMANSTX1A_HUMANBioGRID, HPRD12101244 12590134 details
SYTL4_HUMANFCHO1_HUMANBioGRID32296183 details
SYTL4_HUMANSTX3_HUMANBioGRID24700782 26553929 details
SYTL4_HUMANSTX2_HUMANBioGRID24700782 details
SYTL4_HUMANRB11A_HUMANBioGRID26553929 34079125 details
SYTL4_HUMANMYO5B_HUMANBioGRID26553929 details
SYTL4_HUMANRAB3B_HUMANBioGRID26553929 34079125 details
SYTL4_HUMANTBC30_HUMANBioGRID26553929 details
SYTL4_HUMANEVI5_HUMANBioGRID26553929 details
SYTL4_HUMANINS_HUMANHPRD10497219 details
SYTL4_HUMANSYTL4_HUMANHPRD12176990 details