Entity Details

Primary name PPE1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO14829
EntryNamePPE1_HUMAN
FullNameSerine/threonine-protein phosphatase with EF-hands 1
TaxID9606
Evidenceevidence at protein level
Length653
SequenceStatuscomplete
DateCreated2001-01-11
DateModified2021-06-02

Ontological Relatives

GenesPPEF1

GO terms

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GOName
GO:0004722 protein serine/threonine phosphatase activity
GO:0005506 iron ion binding
GO:0005509 calcium ion binding
GO:0005634 nucleus
GO:0005829 cytosol
GO:0006470 protein dephosphorylation
GO:0022400 regulation of rhodopsin mediated signaling pathway
GO:0030145 manganese ion binding
GO:0050906 detection of stimulus involved in sensory perception
GO:0106306 protein serine phosphatase activity
GO:0106307 protein threonine phosphatase activity

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000048 IQ motif, EF-hand binding siteSiteBinding site
IPR002048 EF-hand domainDomainDomain
IPR004843 Calcineurin-like phosphoesterase domain, ApaH typeDomainDomain
IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphataseDomainDomain
IPR011992 EF-hand domain pairFamilyHomologous superfamily
IPR012008 Serine/threonine-protein phosphatase with EF-handsFamilyFamily
IPR013235 PPP domainDomainDomain
IPR018247 EF-Hand 1, calcium-binding siteSiteBinding site

Diseases

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