Entity Details

Primary name ACOX2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ99424
EntryNameACOX2_HUMAN
FullNamePeroxisomal acyl-coenzyme A oxidase 2
TaxID9606
Evidenceevidence at protein level
Length681
SequenceStatuscomplete
DateCreated2001-11-02
DateModified2021-06-02

Ontological Relatives

GenesACOX2

GO terms

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GOName
GO:0000038 very long-chain fatty acid metabolic process
GO:0003997 acyl-CoA oxidase activity
GO:0005504 fatty acid binding
GO:0005777 peroxisome
GO:0005782 peroxisomal matrix
GO:0005829 cytosol
GO:0006699 bile acid biosynthetic process
GO:0008104 protein localization
GO:0010942 positive regulation of cell death
GO:0016401 palmitoyl-CoA oxidase activity
GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase
GO:0033791 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity
GO:0042803 protein homodimerization activity
GO:0043231 intracellular membrane-bounded organelle
GO:0050660 flavin adenine dinucleotide binding
GO:0055088 lipid homeostasis
GO:0071949 FAD binding
GO:1902884 positive regulation of response to oxidative stress

Subcellular Location

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Subcellular Location
Peroxisome

Domains

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DomainNameCategoryType
IPR002655 Acyl-CoA oxidase, C-terminalDomainDomain
IPR006091 Acyl-CoA oxidase/dehydrogenase, central domainDomainDomain
IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamilyFamilyHomologous superfamily
IPR012258 Acyl-CoA oxidaseFamilyFamily
IPR029320 Acyl-coenzyme A oxidase, N-terminalDomainDomain
IPR036250 Acyl-CoA dehydrogenase-like, C-terminalFamilyHomologous superfamily
IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
ACOX2_HUMANDYLT1_HUMANBioGRID, IntAct32296183 details
ACOX2_HUMANPEX5_HUMANBioGRID20178365 details
ACOX2_HUMANCLK1_HUMANBioGRID26167880 details