Entity Details

Primary name BCDO1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9HAY6
EntryNameBCDO1_HUMAN
FullNameBeta,beta-carotene 15,15'-dioxygenase
TaxID9606
Evidenceevidence at protein level
Length547
SequenceStatuscomplete
DateCreated2003-10-10
DateModified2021-06-02

Ontological Relatives

GenesBCO1

GO terms

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GOName
GO:0001523 retinoid metabolic process
GO:0003834 beta-carotene 15,15'-monooxygenase activity
GO:0005829 cytosol
GO:0010436 carotenoid dioxygenase activity
GO:0016121 carotene catabolic process
GO:0035238 vitamin A biosynthetic process
GO:0042572 retinol metabolic process
GO:0042574 retinal metabolic process
GO:0046872 metal ion binding
GO:1901810 beta-carotene metabolic process

Subcellular Location

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Domains

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DomainNameCategoryType
IPR004294 Carotenoid oxygenaseFamilyFamily

Diseases

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Disease IDSourceNameDescription
115300 OMIMHypercarotenemia and vitamin A deficiency, autosomal dominant (HCVAD)A disorder characterized by increased serum beta-carotene, decreased conversion of beta-carotene to vitamin A and decreased serum vitamin A. The disease is caused by variants affecting the gene represented in this entry.

Drugs

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DrugNameSourceType
DB06755 Beta caroteneSwissprotsmall molecule

Interactions

0 interactions

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