Entity Details

Primary name TRPV5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NQA5
EntryNameTRPV5_HUMAN
FullNameTransient receptor potential cation channel subfamily V member 5
TaxID9606
Evidenceevidence at protein level
Length729
SequenceStatuscomplete
DateCreated2005-04-26
DateModified2021-06-02

Ontological Relatives

GenesTRPV5

GO terms

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GOName
GO:0005216 ion channel activity
GO:0005262 calcium channel activity
GO:0005516 calmodulin binding
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006816 calcium ion transport
GO:0016324 apical plasma membrane
GO:0035809 regulation of urine volume
GO:0046872 metal ion binding
GO:0051289 protein homotetramerization
GO:0055074 calcium ion homeostasis
GO:0070588 calcium ion transmembrane transport
GO:0098703 calcium ion import across plasma membrane

Subcellular Location

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Subcellular Location
Apical cell membrane

Domains

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DomainNameCategoryType
IPR002110 Ankyrin repeatRepeatRepeat
IPR005821 Ion transport domainDomainDomain
IPR008344 Transient receptor potential cation channel subfamily V member 5/6FamilyFamily
IPR008346 Transient receptor potential cation channel subfamily V member 5FamilyFamily
IPR020683 Ankyrin repeat-containing domainDomainDomain
IPR024862 Transient receptor potential cation channel subfamily VFamilyFamily
IPR036770 Ankyrin repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB11093 Calcium citrateDrugbanksmall molecule
DB11348 Calcium PhosphateDrugbanksmall molecule
DB14481 Calcium phosphate dihydrateDrugbanksmall molecule