Entity Details

Primary name TYW1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NV66
EntryNameTYW1_HUMAN
FullNameS-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1
TaxID9606
Evidenceevidence at transcript level
Length732
SequenceStatuscomplete
DateCreated2007-04-03
DateModified2021-06-02

Ontological Relatives

GenesTYW1

GO terms

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GOName
GO:0010181 FMN binding
GO:0031591 wybutosine biosynthetic process
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0102521 tRNA-4-demethylwyosine synthase activity

Subcellular Location

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Domains

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DomainNameCategoryType
IPR001094 Flavodoxin-likeDomainDomain
IPR007197 Radical SAMDomainDomain
IPR008254 Flavodoxin/nitric oxide synthaseDomainDomain
IPR013785 Aldolase-type TIM barrelFamilyHomologous superfamily
IPR013917 tRNA wybutosine-synthesisDomainDomain
IPR029039 Flavoprotein-like superfamilyFamilyHomologous superfamily
IPR034556 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthaseFamilyFamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
TYW1_HUMANMMS19_HUMANBioGRID, IntAct22678361 22678362 28178521 details
TYW1_HUMANST7_HUMANBioGRID29395067 details