Entity Details

Primary name KCND3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UK17
EntryNameKCND3_HUMAN
FullNamePotassium voltage-gated channel subfamily D member 3
TaxID9606
Evidenceevidence at protein level
Length655
SequenceStatuscomplete
DateCreated2003-11-07
DateModified2021-06-02

Ontological Relatives

GenesKCND3

GO terms

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GOName
GO:0005249 voltage-gated potassium channel activity
GO:0005250 A-type (transient outward) potassium channel activity
GO:0005886 plasma membrane
GO:0006813 potassium ion transport
GO:0008076 voltage-gated potassium channel complex
GO:0014069 postsynaptic density
GO:0016021 integral component of membrane
GO:0034765 regulation of ion transmembrane transport
GO:0042383 sarcolemma
GO:0043025 neuronal cell body
GO:0043197 dendritic spine
GO:0044325 transmembrane transporter binding
GO:0045211 postsynaptic membrane
GO:0046872 metal ion binding
GO:0051260 protein homooligomerization
GO:0061337 cardiac conduction
GO:0071805 potassium ion transmembrane transport
GO:0086009 membrane repolarization
GO:0086013 membrane repolarization during cardiac muscle cell action potential
GO:0086091 regulation of heart rate by cardiac conduction
GO:0097623 potassium ion export across plasma membrane
GO:0098915 membrane repolarization during ventricular cardiac muscle cell action potential
GO:0098982 GABA-ergic synapse
GO:0099060 integral component of postsynaptic specialization membrane
GO:0099625 ventricular cardiac muscle cell membrane repolarization

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection

Domains

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DomainNameCategoryType
IPR000210 BTB/POZ domainDomainDomain
IPR003131 Potassium channel tetramerisation-type BTB domainDomainDomain
IPR003968 Potassium channel, voltage dependent, KvFamilyFamily
IPR003975 Potassium channel, voltage dependent, Kv4FamilyFamily
IPR004056 Potassium channel, voltage dependent, Kv4.3FamilyFamily
IPR005821 Ion transport domainDomainDomain
IPR011333 SKP1/BTB/POZ domain superfamilyFamilyHomologous superfamily
IPR021645 Shal-type voltage-gated potassium channels, N-terminalDomainDomain
IPR024587 Potassium channel, voltage dependent, Kv4, C-terminalDomainDomain
IPR027359 Voltage-dependent channel domain superfamilyFamilyHomologous superfamily
IPR028325 Voltage-gated potassium channelFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB00228 EnfluraneDrugbanksmall molecule
DB00280 DisopyramideDrugbanksmall molecule
DB00458 ImipramineDrugbanksmall molecule
DB01069 PromethazineDrugbanksmall molecule
DB01110 MiconazoleDrugbanksmall molecule
DB01115 NifedipineDrugbanksmall molecule
DB04855 DronedaroneDrugbanksmall molecule
DB06217 VernakalantDrugbanksmall molecule
DB06637 DalfampridineDrugbanksmall molecule
DB11633 IsavuconazoleDrugbanksmall molecule

Interactions

37 interactions

InteractorPartnerSourcesPublicationsLink
KCND3_HUMANKCIP1_HUMANBioGRID, IntAct17187064 details
KCND3_HUMANSRC_HUMANBioGRID18620005 details
KCND3_HUMANDPP10_HUMANBioGRID22387313 details
KCND3_HUMANAUP1_HUMANBioGRID17725712 details
KCND3_HUMANCDK1_HUMANBioGRID17725712 details
KCND3_HUMANCNBP_HUMANBioGRID17725712 details
KCND3_HUMANCUX1_HUMANBioGRID17725712 details
KCND3_HUMANCASP_HUMANBioGRID17725712 details
KCND3_HUMANDDB1_HUMANBioGRID17725712 details
KCND3_HUMANEMD_HUMANBioGRID17725712 details
KCND3_HUMANEWS_HUMANBioGRID17725712 details
KCND3_HUMANG3BP1_HUMANBioGRID17725712 details
KCND3_HUMANBIP_HUMANBioGRID17725712 details
KCND3_HUMANHNRPF_HUMANBioGRID17725712 details
KCND3_HUMANHSP7C_HUMANBioGRID17725712 details
KCND3_HUMANXRCC6_HUMANBioGRID17725712 details
KCND3_HUMANXRCC5_HUMANBioGRID17725712 details
KCND3_HUMANLBR_HUMANBioGRID17725712 details
KCND3_HUMANNONO_HUMANBioGRID17725712 details
KCND3_HUMANNP1L1_HUMANBioGRID17725712 details
KCND3_HUMANNDUS2_HUMANBioGRID17725712 details
KCND3_HUMANP5CR2_HUMANBioGRID17725712 details
KCND3_HUMANRCN2_HUMANBioGRID17725712 details
KCND3_HUMANRPGF5_HUMANBioGRID17725712 details
KCND3_HUMANRUVB1_HUMANBioGRID17725712 details
KCND3_HUMANTBA1B_HUMANBioGRID17725712 details
KCND3_HUMANTBB2A_HUMANBioGRID17725712 details
KCND3_HUMANQCR2_HUMANBioGRID17725712 details
KCND3_HUMANVPS4A_HUMANBioGRID17725712 details
KCND3_HUMANKCIP2_HUMANBioGRID, HPRD12928444 details
KCND3_HUMANSEM3A_HUMANBioGRID24963029 details
KCND3_HUMANTLR3_HUMANBioGRID30758987 details
KCND3_HUMANSCN1B_HUMANBioGRID30160358 details
KCND3_HUMANKCNH2_HUMANBioGRID29259226 details
KCND3_HUMANHSP74_HUMANBioGRID29259226 details
KCND3_HUMANHS90A_HUMANBioGRID29259226 details
KCND3_HUMANKCND3_HUMANHPRD14980207 details