Entity Details

Primary name RNAS1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP07998
EntryNameRNAS1_HUMAN
FullNameRibonuclease pancreatic
TaxID9606
Evidenceevidence at protein level
Length156
SequenceStatuscomplete
DateCreated1988-08-01
DateModified2021-06-02

Ontological Relatives

GenesRNASE1

GO terms

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GOName
GO:0003676 nucleic acid binding
GO:0004522 ribonuclease A activity
GO:0004540 ribonuclease activity
GO:0016829 lyase activity
GO:0070062 extracellular exosome
GO:0090501 RNA phosphodiester bond hydrolysis

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR001427 Pancreatic ribonucleaseFamilyFamily
IPR023411 Ribonuclease A, active siteSiteActive site
IPR023412 Ribonuclease A-domainDomainDomain
IPR036816 Ribonuclease A-like domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00128 Aspartic acidDrugbanksmall molecule
DB00536 GuanidineDrugbanksmall molecule
DB01812 Adenosine 3',5'-diphosphateDrugbanksmall molecule
DB01842 3'-Phosphate-Adenosine-5'-DiphosphateDrugbanksmall molecule
DB01942 Formic acidDrugbanksmall molecule
DB01961 Cytidine 3'-monophosphateDrugbanksmall molecule
DB02098 Adenosine-2'-5'-DiphosphateDrugbanksmall molecule
DB02363 2'-Monophosphoadenosine-5'-DiphosphateDrugbanksmall molecule
DB02573 2'-deoxycytidine-2'-deoxyadenosine-3',5'-monophosphateDrugbanksmall molecule
DB02714 3'-UridinemonophosphateDrugbanksmall molecule
DB02805 Arabinouridine 3'-phosphateDrugbanksmall molecule
DB02987 Cysteine-S-acetamideDrugbanksmall molecule
DB03155 2'-fluoro-2'-deoxyuridine 3'-monophosphateDrugbanksmall molecule
DB03186 Adenylate-3'-phosphate-[[2'-deoxy-uridine-5'-phosphate]-3'-phosphate]Drugbanksmall molecule
DB03326 Deoxycytidylyl-3',5'-guanosineDrugbanksmall molecule
DB03447 Uridylyl-2'-5'-phospho-adenosineDrugbanksmall molecule
DB03448 2'-Deoxyuridine 3'-MonophosphateDrugbanksmall molecule
DB03512 Uridine-2',3'-vanadateDrugbanksmall molecule
DB03726 Purine Riboside-5'-MonophosphateDrugbanksmall molecule
DB03765 2'-cytidylic acidDrugbanksmall molecule
DB03792 5-AminouracilDrugbanksmall molecule
DB03900 tert-butanolDrugbanksmall molecule
DB04272 Citric acidDrugbanksmall molecule
DB04464 N-FormylmethionineDrugbanksmall molecule
DB04514 Uridylyl-2'-5'-phospho-guanosineDrugbanksmall molecule
DB08596 5'-deoxy-5'-piperidin-1-ylthymidineDrugbanksmall molecule
DB08661 1-(2,5-dideoxy-5-pyrrolidin-1-yl-beta-L-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dioneDrugbanksmall molecule

Interactions

4 interactions