Entity Details

Primary name AMPN_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP15144
EntryNameAMPN_HUMAN
FullNameAminopeptidase N
TaxID9606
Evidenceevidence at protein level
Length967
SequenceStatuscomplete
DateCreated1990-04-01
DateModified2021-06-02

Ontological Relatives

GenesANPEP

GO terms

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GOName
GO:0001525 angiogenesis
GO:0001618 virus receptor activity
GO:0004177 aminopeptidase activity
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005765 lysosomal membrane
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
GO:0005886 plasma membrane
GO:0006508 proteolysis
GO:0007165 signal transduction
GO:0008217 regulation of blood pressure
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
GO:0016021 integral component of membrane
GO:0030154 cell differentiation
GO:0030667 secretory granule membrane
GO:0038023 signaling receptor activity
GO:0042277 peptide binding
GO:0043171 peptide catabolic process
GO:0043312 neutrophil degranulation
GO:0070006 metalloaminopeptidase activity
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolaseFamilyFamily
IPR014782 Peptidase M1, membrane alanine aminopeptidaseDomainDomain
IPR024571 ERAP1-like C-terminal domainDomainDomain
IPR034016 Aminopeptidase N-typeFamilyFamily
IPR042097 Aminopeptidase N-like , N-terminalFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00973 EzetimibeDrugbanksmall molecule
DB06196 IcatibantDrugbanksmall molecule
DB06773 Human calcitoninDrugbankbiotech

Interactions

3 interactions