Entity Details

Primary name KDM5A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP29375
EntryNameKDM5A_HUMAN
FullNameLysine-specific demethylase 5A
TaxID9606
Evidenceevidence at protein level
Length1690
SequenceStatuscomplete
DateCreated1992-12-01
DateModified2021-06-02

Ontological Relatives

GenesKDM5A

GO terms

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GOName
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003713 transcription coactivator activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0006338 chromatin remodeling
GO:0007283 spermatogenesis
GO:0008270 zinc ion binding
GO:0008584 male gonad development
GO:0032452 histone demethylase activity
GO:0032922 circadian regulation of gene expression
GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)
GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)
GO:0034720 histone H3-K4 demethylation
GO:0035064 methylated histone binding
GO:0042393 histone binding
GO:0045893 positive regulation of transcription, DNA-templated
GO:0051090 regulation of DNA-binding transcription factor activity
GO:0051213 dioxygenase activity
GO:1901726 negative regulation of histone deacetylase activity

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001606 ARID DNA-binding domainDomainDomain
IPR001965 Zinc finger, PHD-typeDomainDomain
IPR003347 JmjC domainDomainDomain
IPR003349 JmjN domainDomainDomain
IPR004198 Zinc finger, C5HC2-typeDomainDomain
IPR011011 Zinc finger, FYVE/PHD-typeFamilyHomologous superfamily
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR013637 Lysine-specific demethylase-like domainDomainDomain
IPR019786 Zinc finger, PHD-type, conserved siteSiteConserved site
IPR019787 Zinc finger, PHD-fingerDomainDomain
IPR036431 ARID DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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