Entity Details

Primary name SC5A2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP31639
EntryNameSC5A2_HUMAN
FullNameSodium/glucose cotransporter 2
TaxID9606
Evidenceevidence at transcript level
Length672
SequenceStatuscomplete
DateCreated1993-07-01
DateModified2021-06-02

Ontological Relatives

GenesSLC5A2

GO terms

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GOName
GO:0000017 alpha-glucoside transport
GO:0005362 low-affinity glucose:sodium symporter activity
GO:0005412 glucose:sodium symporter activity
GO:0005886 plasma membrane
GO:0005975 carbohydrate metabolic process
GO:0006814 sodium ion transport
GO:0008645 hexose transmembrane transport
GO:0015151 alpha-glucoside transmembrane transporter activity
GO:0016021 integral component of membrane
GO:0055056 D-glucose transmembrane transporter activity
GO:0070062 extracellular exosome
GO:0098708 glucose import across plasma membrane
GO:0098719 sodium ion import across plasma membrane

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR001734 Sodium/solute symporterFamilyFamily
IPR018212 Sodium/solute symporter, conserved siteSiteConserved site
IPR038377 Sodium/glucose symporter superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01914 D-glucoseSwissprotsmall molecule
DB06292 DapagliflozinDrugbanksmall molecule
DB08907 CanagliflozinDrugbanksmall molecule
DB09038 EmpagliflozinDrugbanksmall molecule
DB11827 ErtugliflozinDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
SC5A2_HUMANAQP2_HUMANBioGRID28931009 details