Entity Details

Primary name MA2A2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP49641
EntryNameMA2A2_HUMAN
FullNameAlpha-mannosidase 2x
TaxID9606
Evidenceevidence at transcript level
Length1150
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesMAN2A2

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0004559 alpha-mannosidase activity
GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity
GO:0006013 mannose metabolic process
GO:0006486 protein glycosylation
GO:0006491 N-glycan processing
GO:0006517 protein deglycosylation
GO:0016021 integral component of membrane
GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds
GO:0030246 carbohydrate binding
GO:0046872 metal ion binding

Subcellular Location

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Subcellular Location
Golgi apparatus membrane

Domains

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DomainNameCategoryType
IPR000602 Glycoside hydrolase family 38, N-terminal domainDomainDomain
IPR011013 Galactose mutarotase-like domain superfamilyFamilyHomologous superfamily
IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrelFamilyHomologous superfamily
IPR011682 Glycosyl hydrolase family 38, C-terminalDomainDomain
IPR013780 Glycosyl hydrolase, all-betaFamilyHomologous superfamily
IPR015341 Glycoside hydrolase family 38, central domainDomainDomain
IPR027291 Glycoside hydrolase 38, N-terminal domain superfamilyFamilyHomologous superfamily
IPR028995 Glycoside hydrolase families 57/38, central domain superfamilyFamilyHomologous superfamily
IPR037094 Glycoside hydrolase family 38, central domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

6 interactions

InteractorPartnerSourcesPublicationsLink
MA2A2_HUMANCHD3_HUMANBioGRID, HPRD, IntAct16169070 details
MA2A2_HUMANVIME_HUMANBioGRID, HPRD, IntAct16169070 details
MA2A2_HUMANLC7L2_HUMANBioGRID, HPRD, IntAct16169070 details
MA2A2_HUMANGIT1_HUMANBioGRID, HPRD, IntAct16169070 details
MA2A2_HUMANELP1_HUMANBioGRID, HPRD, IntAct16169070 details
MA2A2_HUMANENOB_HUMANBioGRID, IntAct23414517 details