Entity Details

Primary name GFRA1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP56159
EntryNameGFRA1_HUMAN
FullNameGDNF family receptor alpha-1
TaxID9606
Evidenceevidence at protein level
Length465
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesGFRA1

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0005102 signaling receptor binding
GO:0005771 multivesicular body
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0007166 cell surface receptor signaling pathway
GO:0007399 nervous system development
GO:0007411 axon guidance
GO:0009897 external side of plasma membrane
GO:0016167 glial cell-derived neurotrophic factor receptor activity
GO:0019898 extrinsic component of membrane
GO:0031225 anchored component of membrane
GO:0038023 signaling receptor activity
GO:0043235 receptor complex
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cell membrane
Endosome
Golgi apparatus

Domains

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DomainNameCategoryType
IPR003438 Glial cell line-derived neurotrophic factor receptorFamilyFamily
IPR003503 Glial cell line-derived neurotrophic factor receptor, alpha 1FamilyFamily
IPR016017 GDNF/GAS1DomainDomain
IPR017372 Glial cell line-derived neurotrophic factor receptor, alpha 1/2FamilyFamily
IPR037193 GDNF receptor alphaFamilyHomologous superfamily

Diseases

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