Entity Details

Primary name IL1RAPL1
Entity type gene
Source Source Link

Details

PrimaryID11141
RefseqGeneNG_008292
SymbolIL1RAPL1
Nameinterleukin 1 receptor accessory protein like 1
ChromosomeX
LocationXp21.3-p21.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-02-28
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsIRPL1_HUMAN

GO terms

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GOName
GO:0005102 signaling receptor binding
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007165 signal transduction
GO:0009986 cell surface
GO:0010975 regulation of neuron projection development
GO:0016021 integral component of membrane
GO:0030182 neuron differentiation
GO:0030424 axon
GO:0030425 dendrite
GO:0045211 postsynaptic membrane
GO:0045920 negative regulation of exocytosis
GO:0050135 NAD(P)+ nucleosidase activity
GO:0050775 positive regulation of dendrite morphogenesis
GO:0051965 positive regulation of synapse assembly
GO:0061809 NAD+ nucleotidase, cyclic ADP-ribose generating
GO:0071345 cellular response to cytokine stimulus
GO:0097105 presynaptic membrane assembly
GO:0098978 glutamatergic synapse
GO:0099175 regulation of postsynapse organization
GO:0099545 trans-synaptic signaling by trans-synaptic complex
GO:1905606 regulation of presynapse assembly

Diseases

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Disease IDSourceNameDescription
300143 OMIMMental retardation, X-linked 21 (MRX21)A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. Intellectual deficiency is the only primary symptom of non-syndromic X-linked mental retardation, while syndromic mental retardation presents with associated physical, neurological and/or psychiatric manifestations. The disease is caused by variants affecting the gene represented in this entry.

Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
IL1RAPL1NCS1BioGRID, HPRD12783849 details
IL1RAPL1ARHGAP22BioGRID21926414 details
IL1RAPL1PTPRDBioGRID21926414 details
IL1RAPL1CFTRBioGRID, IntAct17110338 details
IL1RAPL1NR3C1BioGRID31182584 details