Entity Details

Primary name NEK10
Entity type gene
Source Source Link

Details

PrimaryID152110
RefseqGene
SymbolNEK10
NameNIMA related kinase 10
Chromosome3
Location3p24.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2002-01-23
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsNEK10_HUMAN

GO terms

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GOName
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005576 extracellular region
GO:0006468 protein phosphorylation
GO:0031954 positive regulation of protein autophosphorylation
GO:0043406 positive regulation of MAP kinase activity
GO:0046872 metal ion binding
GO:0070372 regulation of ERK1 and ERK2 cascade
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:0120197 mucociliary clearance
GO:1902749 regulation of cell cycle G2/M phase transition
GO:1902911 protein kinase complex

Diseases

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Disease IDSourceNameDescription
618781 OMIMCiliary dyskinesia, primary, 44 (CILD44)A form of primary ciliary dyskinesia, a disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia. CILD44 inheritance is autosomal recessive. The disease is caused by variants affecting the gene represented in this entry.

Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
NEK10HSPB1BioGRID, IntAct25277244 details
NEK10MAP3K1BioGRID25260751 details
NEK10FUSUniProt27460707 details
NEK10USP15BioGRID31952546 details