Entity Details

Primary name PRSS12
Entity type gene
Source Source Link

Details

PrimaryID8492
RefseqGeneNG_023350
SymbolPRSS12
Nameserine protease 12
Chromosome4
Location4q26
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-11-07
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsNETR_HUMAN

GO terms

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GOName
GO:0004252 serine-type endopeptidase activity
GO:0005044 scavenger receptor activity
GO:0005886 plasma membrane
GO:0006887 exocytosis
GO:0008236 serine-type peptidase activity
GO:0030424 axon
GO:0030425 dendrite
GO:0031410 cytoplasmic vesicle
GO:0031638 zymogen activation
GO:0043083 synaptic cleft
GO:0043195 terminal bouton

Diseases

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Disease IDSourceNameDescription
249500 OMIMMental retardation, autosomal recessive 1 (MRT1)A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs. The disease is caused by variants affecting the gene represented in this entry.

Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
PRSS12CNTLNBioGRID, IntAct26496610 details
PRSS12PRPF40ABioGRID, IntAct26496610 details
PRSS12PPIL3BioGRID, IntAct26496610 details
PRSS12SH3PXD2ABioGRID26496610 details