Entity Details

Primary name RIPOR2
Entity type gene
Source Source Link

Details

PrimaryID9750
RefseqGeneNG_051606
SymbolRIPOR2
NameRHO family interacting cell polarization regulator 2
Chromosome6
Location6p22.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-01-03
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsRIPR2_HUMAN

GO terms

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GOName
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0006935 chemotaxis
GO:0007155 cell adhesion
GO:0007162 negative regulation of cell adhesion
GO:0007605 sensory perception of sound
GO:0016324 apical plasma membrane
GO:0030175 filopodium
GO:0032420 stereocilium
GO:0035024 negative regulation of Rho protein signal transduction
GO:0042130 negative regulation of T cell proliferation
GO:0042802 identical protein binding
GO:0045184 establishment of protein localization
GO:0045663 positive regulation of myoblast differentiation
GO:0048741 skeletal muscle fiber development
GO:0051260 protein homooligomerization
GO:0051491 positive regulation of filopodium assembly
GO:0060088 auditory receptor cell stereocilium organization
GO:0060171 stereocilium membrane
GO:0071260 cellular response to mechanical stimulus
GO:0071889 14-3-3 protein binding
GO:0090023 positive regulation of neutrophil chemotaxis
GO:1901673 regulation of mitotic spindle assembly
GO:1901741 positive regulation of myoblast fusion
GO:1903904 negative regulation of establishment of T cell polarity
GO:1905872 negative regulation of protein localization to cell leading edge
GO:1990869 cellular response to chemokine
GO:2000114 regulation of establishment of cell polarity
GO:2000391 positive regulation of neutrophil extravasation
GO:2000405 negative regulation of T cell migration
GO:2001107 negative regulation of Rho guanyl-nucleotide exchange factor activity

Diseases

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Disease IDSourceNameDescription
616515 OMIMDeafness, autosomal recessive, 104 (DFNB104)A form of non-syndromic sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. The disease is caused by variants affecting the gene represented in this entry.

Interactions

12 interactions