Entity Details

Primary name SOSD1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6X4U4
EntryNameSOSD1_HUMAN
FullNameSclerostin domain-containing protein 1
TaxID9606
Evidenceevidence at protein level
Length206
SequenceStatuscomplete
DateCreated2005-03-29
DateModified2021-06-02

Ontological Relatives

GenesSOSTDC1

GO terms

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GOName
GO:0005615 extracellular space
GO:0007389 pattern specification process
GO:0010454 negative regulation of cell fate commitment
GO:0016055 Wnt signaling pathway
GO:0030178 negative regulation of Wnt signaling pathway
GO:0030514 negative regulation of BMP signaling pathway
GO:0031069 hair follicle morphogenesis
GO:0036122 BMP binding
GO:0042475 odontogenesis of dentin-containing tooth
GO:0045662 negative regulation of myoblast differentiation
GO:0060648 mammary gland bud morphogenesis
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0098821 BMP receptor activity
GO:2000016 negative regulation of determination of dorsal identity

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR006207 Cystine knot, C-terminalDomainDomain
IPR008835 Sclerostin/Sclerostin domain-containing protein 1FamilyFamily
IPR029034 Cystine-knot cytokineFamilyHomologous superfamily

Diseases

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