Entity Details

Primary name HORN_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ86YZ3
EntryNameHORN_HUMAN
FullNameHornerin
TaxID9606
Evidenceevidence at protein level
Length2850
SequenceStatuscomplete
DateCreated2004-03-15
DateModified2021-06-02

Ontological Relatives

GenesHRNR

GO terms

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GOName
GO:0001533 cornified envelope
GO:0005509 calcium ion binding
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0031424 keratinization
GO:0035578 azurophil granule lumen
GO:0036457 keratohyalin granule
GO:0043163 cell envelope organization
GO:0043312 neutrophil degranulation
GO:0046914 transition metal ion binding
GO:0048471 perinuclear region of cytoplasm
GO:0061436 establishment of skin barrier
GO:0062023 collagen-containing extracellular matrix
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cytoplasmic granule

Domains

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DomainNameCategoryType
IPR001751 S100/Calbindin-D9k, conserved siteSiteConserved site
IPR002048 EF-hand domainDomainDomain
IPR011992 EF-hand domain pairFamilyHomologous superfamily
IPR013787 S100/CaBP-9k-type, calcium binding, subdomainDomainDomain
IPR018247 EF-Hand 1, calcium-binding siteSiteBinding site
IPR033201 HornerinFamilyFamily
IPR034325 S-100DomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB01593 ZincDrugbanksmall molecule
DB14487 Zinc acetateDrugbanksmall molecule